Pinto C, Lele M V, Joglekar A S, Panwar V S, Dhavale H S
Department of Psychiatry, BYL Nair Hospital and TN Medical College, Mumbai-8.
J Assoc Physicians India. 2000 Jun;48(6):589-93.
A lot of research has pointed to a complex interaction between stressful life events, psychiatric morbidity and the irritable bowel syndrome (IBS).
The present study aimed to determine the: stressful life-events in patients with irritable bowel syndrome patients in comparison to normal controls; effect of these events in causing clinically significant anxiety and depression; and the effect of psychopathology i.e. anxiety and depression on coping skills in these patients.
Thirty patients with irritable bowel syndrome were compared with thirty matched normal controls, on the presumptive stressful life events scale and the mechanisms of coping scale. Further, among the irritable bowel syndrome patient group, the anxious and depressed subgroups were separated from the non-anxious and non-depressed subgroups using the hospital anxiety and depression scale. Positive and negative coping mechanisms between these subgroups were compared.
Significantly higher stress scores were found in the irritable bowel syndrome patient group than normal controls. Not all, but slightly more than fifty percent of irritable bowel syndrome had definite and clinically significant anxiety and/or depression. Those IBS patients with either definite depression tended to use predominantly negative coping styles as compared to those IBS patients without anxiety or depression.
Stressful life-event scores are significantly higher in IBS patients than in normal controls. Although not all of these patients have anxiety and/or depression, a significant number of patients show evidence of the same. Presence or absence of anxiety and/or depression influences how the patient with IBS copes with illness. Therefore, though further studies on the issue are required, we suggested that, as a supplement to medical management, recognition and treatment of anxiety and depression in this subgroup of IBS patients with psychotropic drugs and cognitive therapy for gaining more positive coping skills, may require special attention in the management of irritable bowel syndrome.
大量研究指出,应激性生活事件、精神疾病发病率与肠易激综合征(IBS)之间存在复杂的相互作用。
本研究旨在确定:与正常对照组相比,肠易激综合征患者的应激性生活事件;这些事件在引起具有临床意义的焦虑和抑郁方面的作用;以及精神病理学(即焦虑和抑郁)对这些患者应对技巧的影响。
在假定的应激性生活事件量表和应对机制量表上,将30例肠易激综合征患者与30例匹配的正常对照组进行比较。此外,在肠易激综合征患者组中,使用医院焦虑和抑郁量表将焦虑和抑郁亚组与非焦虑和非抑郁亚组区分开来。比较这些亚组之间的积极和消极应对机制。
肠易激综合征患者组的应激得分显著高于正常对照组。并非所有肠易激综合征患者,但略超过50%的患者有明确且具有临床意义的焦虑和/或抑郁。与无焦虑或抑郁的肠易激综合征患者相比,那些有明确抑郁的肠易激综合征患者倾向于主要使用消极应对方式。
肠易激综合征患者的应激性生活事件得分显著高于正常对照组。虽然并非所有这些患者都有焦虑和/或抑郁,但相当数量的患者有此证据。焦虑和/或抑郁的存在与否会影响肠易激综合征患者应对疾病的方式。因此,尽管需要对此问题进行进一步研究,但我们建议,作为药物治疗的补充,对于这一亚组有焦虑和抑郁的肠易激综合征患者,使用精神药物和认知疗法来识别和治疗焦虑和抑郁以获得更积极的应对技巧,在肠易激综合征的管理中可能需要特别关注。