急性小脑性共济失调中的小脑刺激
Cerebellar stimulation in acute cerebellar ataxia.
作者信息
Matsunaga K, Uozumi T, Hashimoto T, Tsuji S
机构信息
Department of Neurology, University of Occupational and Environmental Health, School of Medicine, Yahatanishi-ku, Kitakyushu City 807-8555, Japan.
出版信息
Clin Neurophysiol. 2001 Apr;112(4):619-22. doi: 10.1016/s1388-2457(01)00476-x.
OBJECTIVES
To report follow-up studies of cerebellar stimulation in patients with acute cerebellar ataxia (ACA).
METHODS
We studied two patients with ACA. One patient also had decreased deep sensations in the feet due to combined diseases such as diabetic polyneuropathy and lumbosacral radiculopathies. We applied the technique of electrical stimulation over the cerebellum which was reported previously (Ugawa et al., J Physiol 441 (1991a) 57).
RESULTS
Conditioning stimulation over the cerebellum did not reduce the size of motor-evoked potentials to test magnetic stimulation of the motor cortex at conditioning-test intervals of 5, 6, and 7 ms in the acute stage in both patients. However, normal suppression was recognized in the recovery stage in both patients.
CONCLUSIONS
This technique was useful for follow-up evaluation of cerebellar function in patients with ACA and was also useful for distinguishing cerebellar ataxia from sensory ataxia in a patient with combined diseases.
目的
报告急性小脑性共济失调（ACA）患者小脑刺激的随访研究。
方法
我们研究了两名ACA患者。其中一名患者因糖尿病性多发性神经病和腰骶神经根病等合并疾病，足部深部感觉也减退。我们应用了先前报道的小脑电刺激技术（Ugawa等人，《生理学杂志》441（1991a）57）。
结果
在两名患者的急性期，当条件刺激与测试刺激的间隔为5、6和7毫秒时，小脑的条件刺激并未减小运动诱发电位的幅度，该运动诱发电位是通过对运动皮层进行磁刺激来测试的。然而，两名患者在恢复阶段均出现了正常的抑制现象。
结论
该技术有助于对ACA患者的小脑功能进行随访评估，也有助于区分合并疾病患者的小脑性共济失调和感觉性共济失调。
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