Puskar D, Balagović I, Filipović A, Knezović N, Kopjar M, Huis M, Gilja I
Department of Surgery and Urology, General Hospital, Trg. Domjanića 6, CRO-49210 Zabok, Croatia.
Eur Urol. 2001 Mar;39(3):260-3. doi: 10.1159/000052449.
We present the incidence and results of treatment of symptomatic physiologic hydronephrosis in 3,400 pregnant women.
We analyzed 103 consecutive women who presented with clinical signs and symptoms related to the upper urinary system. Renal sonography, urinalysis, serum creatinine levels, white blood cell (WBC) count, and urine culture were done in all patients at first visit and repeated at least once a month until 1 month after delivery. In patients who manifested acute pyelonephritis, urinalysis, WBC count, erythrocyte sedimentation rate and C-reactive protein levels were repeated every 3 days until normalization, and urine culture as well as renal sonography were performed once a week until 1 month after delivery. Conservative measures (positioning, analgesia, antibiotics) were performed in all patients with symptomatic physiologic hydronephrosis. If the patient's condition was refractory to medical management, drainage of the ureter with a double pigtail stent was performed.
Conservative measures were successful in 97 (94%) of 103 patients but 6 (6%) patients had ongoing signs and symptoms of acute pyelonephritis progressing to urosepsis. In all of them, antibiotics were continued and a double pigtail stent was placed resulting in fast regression of symptoms, curing of renal infection and progress of the pregnancies to the term with vaginal delivery.
Symptomatic hydronephrosis in pregnancy can be treated conservatively. If the patient's condition is refractory to medical management, an internal drainage with double pigtail stent may be necessary.
我们呈现了3400例孕妇中症状性生理性肾积水的发病率及治疗结果。
我们分析了103例连续出现与上泌尿系统相关临床症状和体征的女性患者。所有患者首次就诊时均进行了肾脏超声检查、尿液分析、血清肌酐水平、白细胞(WBC)计数及尿培养,并在产后1个月前至少每月重复检查一次。对于表现为急性肾盂肾炎的患者,每3天重复进行尿液分析、WBC计数、红细胞沉降率及C反应蛋白水平检查直至恢复正常,每周进行一次尿培养及肾脏超声检查直至产后1个月。对所有有症状性生理性肾积水的患者采取保守措施(体位调整、镇痛、抗生素治疗)。如果患者病情对药物治疗无效,则采用双猪尾支架进行输尿管引流。
103例患者中有97例(94%)保守治疗成功,但有6例(6%)患者持续存在急性肾盂肾炎症状并进展为尿脓毒症。对所有这些患者继续使用抗生素并置入双猪尾支架,症状迅速缓解,肾脏感染治愈,妊娠进展至足月并经阴道分娩。
妊娠期症状性肾积水可采用保守治疗。如果患者病情对药物治疗无效,则可能需要使用双猪尾支架进行内引流。