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脑灌注成像方法学。

Methodology of brain perfusion imaging.

作者信息

Barbier E L, Lamalle L, Décorps M

机构信息

Laboratoire mixte INSERM U438, Université Joseph Fourier: RMN Bioclinique, LRC-CEA, Hôpital Albert Michallon, Grenoble, France.

出版信息

J Magn Reson Imaging. 2001 Apr;13(4):496-520. doi: 10.1002/jmri.1073.

DOI:10.1002/jmri.1073
PMID:11276094
Abstract

Numerous techniques have been proposed in the last 15 years to measure various perfusion-related parameters in the brain. In particular, two approaches have proven extremely successful: injection of paramagnetic contrast agents for measuring cerebral blood volumes (CBV) and arterial spin labeling (ASL) for measuring cerebral blood flows (CBF). This review presents the methodology of the different magnetic resonance imaging (MRI) techniques in use for CBV and CBF measurements and briefly discusses their limitations and potentials.

摘要

在过去15年里,人们提出了许多技术来测量大脑中各种与灌注相关的参数。特别是,有两种方法已被证明极为成功:注射顺磁性造影剂以测量脑血容量(CBV),以及动脉自旋标记(ASL)以测量脑血流量(CBF)。本综述介绍了用于测量CBV和CBF的不同磁共振成像(MRI)技术的方法,并简要讨论了它们的局限性和潜力。

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