Ramalho A C, Lazaretti-Castro M, Hauache O, Vieira J G, Takata E, Cafalli F, Tavares F
Escola Paulista de Medicina, Universidade Federal de São Paulo, Brazil.
Sao Paulo Med J. 2001 Mar;119(2):48-53. doi: 10.1590/s1516-31802001000200002.
It is believed that about 25% of menopausal women in the USA will exhibit some kind of fracture as a consequence of osteoporosis. Fractures of the proximal femur are associated with a greater number of deaths and disabilities and higher medical expenses than all the other osteoporotic fractures together.
To study the clinical and epidemiological features of patients with proximal femur fracture in hospitals in São Paulo.
Transversal and retrospective study. LOCAL: Hospital São Paulo and Hospital Servidor Público Estadual "Francisco Morato Oliveira".
Patients aged sixty-five years or more hospitalized because of proximal femur fracture, from March to November 1996 (N = 73). This group was compared to patients of the same age without fracture of the proximal femur.
Evaluation of weight, height, body mass index; lifestyle habits (physical activity at home, ingestion of dairy calcium, drinking of coffee, smoking habit), gynecological history (ages at menarche and menopause, number of pregnancies and lactations), previous morbidity, use of medications, history of previous fractures, family history of osteoporosis.
The comparison of the different data regarding lifestyle habits between the two groups was made using the chi-squared test. Other data were analyzed using the Mann--Whitney test. P pound 0.05 was considered significant.
We noted a predominance of proximal femur fracture among females in relation to males (a female/male ratio of 3.3:1) with a progressive increase in the frequency of proximal femur fracture with age in both sexes. The group with proximal femur fracture, in comparison with the control group, showed a lower body mass index, less physical activity, and a greater number of pregnancies and lactations. Other data were not different.
In accordance with the literature, we found a predomination of proximal femur fracture in women in relation to men, and a favorable effect of higher body mass index and physical activity for decreasing the frequency of proximal femur fracture. We also discuss the role of pregnancies and lactation on the frequency of proximal femur fracture.
据信,美国约25%的绝经后女性会因骨质疏松症而出现某种骨折。股骨近端骨折与更多的死亡和残疾以及比所有其他骨质疏松性骨折加起来更高的医疗费用相关。
研究圣保罗医院股骨近端骨折患者的临床和流行病学特征。
横断面和回顾性研究。地点:圣保罗医院和州立公务员医院“弗朗西斯科·莫拉托·奥利维拉”。
1996年3月至11月因股骨近端骨折住院的65岁及以上患者(N = 73)。将该组与同龄无股骨近端骨折的患者进行比较。
评估体重、身高、体重指数;生活习惯(在家中的体育活动、摄入乳制品钙、喝咖啡、吸烟习惯)、妇科病史(初潮和绝经年龄、怀孕和哺乳次数)、既往发病率、用药情况、既往骨折史、骨质疏松症家族史。
使用卡方检验对两组之间关于生活习惯的不同数据进行比较。其他数据使用曼-惠特尼检验进行分析。P≤0.05被认为具有统计学意义。
我们注意到女性股骨近端骨折相对于男性占优势(女性/男性比例为3.3:1),并且两性中股骨近端骨折的频率随年龄逐渐增加。与对照组相比,股骨近端骨折组的体重指数较低、体育活动较少、怀孕和哺乳次数较多。其他数据无差异。
与文献一致,我们发现女性股骨近端骨折相对于男性占优势,并且较高的体重指数和体育活动对降低股骨近端骨折频率有有利影响。我们还讨论了怀孕和哺乳对股骨近端骨折频率的作用。