Synthesis and antitumor activity of novel paclitaxel-chlorambucil hybrids.
作者信息
Wittman M D, Kadow J F, Vyas D M, Lee F L, Rose W C, Long B H, Fairchild C, Johnston K
机构信息
Discovery Chemistry, Bristol-Myers Squibb Pharmaceutical Research Institute, Wallingford, CT 06492-7660, USA.
出版信息
Bioorg Med Chem Lett. 2001 Mar 26;11(6):811-4. doi: 10.1016/s0960-894x(01)00067-1.
Abstract
The syntheses and antitumor activity of three paclitaxel-chlorambucil hybrids are presented. Hybrid 3 showed significant in vivo efficacy.
摘要
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