Sankaran S, Lucas C, Walt A J
J Trauma. 1975 Apr;15(4):290-6. doi: 10.1097/00005373-197504000-00005.
Experimental studies in dogs were performed to develop a model simulating clinical patients with penetrating wounds of the major abdominal vessels who develop sudden cardiac arrest following laparotomy and decompression of an acute massive hemoperitoneum. Hypovolemic dogs with a saline-distended tense abdomen and major arterial bleeding after laparotomy develop a sudden deterioration of cardiac function despite raped blood infusion, thus simulating the clinical problem. However, thoracic aortic occlusion before laparotomy and until control of distal arterial bleeding prevented such a cardiovascular collapse. Increased intra-abdominal pressure it itself was determental to cardiovascular function; its sudden release by laparotomy was associated with an improvement in cardiovascular function. An approach of thoracic aortic control before laparotomy is recommended in patients with acute massive hemoperitoneum who remain hypotensive before laparotomy.
在犬类身上进行了实验研究，以建立一个模型，模拟临床中主要腹部血管穿透伤患者，这些患者在剖腹手术及急性大量血腹减压后发生心脏骤停。剖腹手术后出现生理盐水扩张的紧张腹部和主要动脉出血的低血容量犬，尽管快速输血，心脏功能仍会突然恶化，从而模拟了临床问题。然而，在剖腹手术前直至远端动脉出血得到控制之前进行胸主动脉阻断，可防止这种心血管崩溃。腹内压升高本身对心血管功能有害；剖腹手术使其突然释放与心血管功能改善有关。对于在剖腹手术前仍处于低血压状态的急性大量血腹患者，建议在剖腹手术前采用胸主动脉控制的方法。
