Browdie D A, Davis J H, Koplewitz M J, Corday L, Leadbetter A W
J Trauma. 1975 Jun;15(6):515-8. doi: 10.1097/00005373-197506000-00011.
A case of human Clostridium sordelli soft tissue infection is presented. Analysis of this patient's course led to the use of a mouse experimental model for examination of this organism's potential for toxin production. Data thus obtained correlated with that seen in this instance of human infection, indicates that the lethal effects of this organism may be related to the ability to Clostridium sordelli to produce a widespread "toxin-mediated" edema with subsequent marked "third-space" sequestration of fluid.
本文报告了一例人类索氏梭菌软组织感染病例。对该患者病程的分析促使使用小鼠实验模型来检测该菌产生毒素的潜力。由此获得的数据与在该例人类感染中观察到的情况相关，表明该菌的致死作用可能与索氏梭菌产生广泛的“毒素介导”水肿并随后导致明显的液体“第三间隙”隔离的能力有关。
