Hulscher M E, Wensing M, van Der Weijden T, Grol R
Centre for Quality of Care Research (WOK), University of Nijmegen, PO Box 9101, 6500 HB Nijmegen, Netherlands, 6500 HB.
Cochrane Database Syst Rev. 2001(1):CD000362. doi: 10.1002/14651858.CD000362.
Primary care physicians hold a strategic position in delivering preventive services. However discrepancies exist between evidence based guidelines and practice.
To assess the effects of interventions to improve the delivery of preventive services in primary care.
We searched the Cochrane Effective Practice and Organisation of Care Group specialised register (November 1995; August 1999), MEDLINE (1980 to 1995) and hand searched relevant journals.
Randomised trials, controlled before and after studies, and interrupted time series analyses of interventions to improve preventive services by primary care professionals responsible for patient care.
Two researchers independently extracted data and assessed study quality.
Fifty-five studies were included, involving more than 2000 health professionals and 99,000 people, with 83 comparisons between intervention and control groups. Post intervention differences between intervention and control groups varied widely within and across categories of interventions. Most interventions were found to be effective in some studies, but not in others. Five comparisons of group education versus no intervention showed absolute change of preventive services varying between -4% and +31%. Nine comparisons of physician reminders versus no intervention showed absolute change of preventive services varying between 5% and 24%. Fourteen comparisons of multifaceted interventions versus no intervention showed absolute change of preventive services varying between -3% and +64%. Six comparisons of multifaceted interventions versus group education reported absolute changes varying between -31% and +28%. All these comparisons used randomised groups. Ten comparisons of multifaceted interventions versus no intervention used non-randomised groups and showed absolute change of preventive services varying between -5% and +21%. The remaining planned comparisons within categories of interventions contained less than five comparisons.
REVIEWER'S CONCLUSIONS: There is currently no solid basis for assuming that a particular intervention or package of interventions will work. Effective interventions to increase preventive activities in primary care exist, but there is considerable variation in the level of change achieved, with effect sizes usually small or moderate. Tailoring interventions to address specific barriers to change in a particular setting is probably important. Multifaceted interventions may be more effective than single interventions, because more barriers to change can be addressed. Future research should analyse barriers to change and interventions to implement preventive services in more detail, to clarify how interventions relate to specific barriers. Since more complex interventions are likely to be more effective but also more costly, economic evaluations should also be included.
基层医疗医生在提供预防服务方面具有战略地位。然而,循证指南与实际做法之间存在差异。
评估旨在改善基层医疗中预防服务提供的干预措施的效果。
我们检索了Cochrane有效实践与护理组织小组专业注册库(1995年11月;1999年8月)、MEDLINE(1980年至1995年),并手工检索了相关期刊。
针对负责患者护理的基层医疗专业人员改善预防服务的干预措施的随机试验、前后对照研究以及中断时间序列分析。
两名研究人员独立提取数据并评估研究质量。
纳入了55项研究,涉及2000多名卫生专业人员和99000人,干预组与对照组之间有83项比较。干预组与对照组干预后的差异在不同干预类别内和类别间差异很大。大多数干预措施在一些研究中被发现有效,但在其他研究中则不然。5项小组教育与无干预的比较显示,预防服务的绝对变化在-4%至+31%之间。9项医生提醒与无干预的比较显示,预防服务的绝对变化在5%至24%之间。14项多方面干预与无干预的比较显示,预防服务的绝对变化在-3%至+64%之间。6项多方面干预与小组教育的比较报告的绝对变化在-31%至+28%之间。所有这些比较都使用了随机分组。10项多方面干预与无干预的比较使用了非随机分组,显示预防服务的绝对变化在-5%至+21%之间。干预类别内其余计划的比较包含少于5项比较。
目前没有确凿的依据假定某一特定干预措施或一揽子干预措施会起作用。存在有效的干预措施来增加基层医疗中的预防活动,但所实现的变化程度存在相当大的差异,效应大小通常较小或中等。针对特定环境中变革的具体障碍量身定制干预措施可能很重要。多方面干预可能比单一干预更有效,因为可以解决更多的变革障碍。未来的研究应更详细地分析变革障碍和实施预防服务的干预措施,以阐明干预措施与具体障碍之间的关系。由于更复杂的干预措施可能更有效但成本也更高,因此也应纳入经济评估。