Little C V, Parsons T
Institute of Health & Community Studies, Bournemouth University, Bournemouth House, Bournemouth University, 17 Christchurch Road, Bournemouth, Dorset, UK, BH1 3LG.
Cochrane Database Syst Rev. 2001(1):CD002947. doi: 10.1002/14651858.CD002947.
The increasing popularity of complementary and alternative medicine appears to be particularly evident amongst people with chronic disease. In the treatment of osteoarthritis, one therapy that has been identified as having potential benefit, is herbal medicine (phytotherapy).
To determine the effectiveness of herbal therapies in treating osteoarthritis.
Databases for mainstream and complementary medicine were searched using terms to include all forms of arthritis combined with herbal medicine. We searched the following electronic databases: MEDLINE, EMBASE, CISCOM, AMED, CINAHL, Cochrane Controlled Trials Register (CCTR), Cochrane Musculoskeletal specialized register, Dissertation Abstracts, BIDS ISI and the Cochrane Complementary Medicine Fields Specialized Register. We also searched the reference lists from retrieved trials.
All randomized trials of herbal interventions in osteoarthritis, compared to placebo. Studies were included according to the a priori protocol and agreement between two reviewers who independently read each selected paper for content and for assessment of quality. Papers of any language were included.
Data were extracted independently by the same two reviewers.
Five studies (four different herbal interventions) met the review criteria. Two studies were suitable for data pooling. It was not possible to draw firm conclusions from the single studies but two studies of avocado/soybean unsaponifiables showed beneficial effects on functional index, pain, intake of NSAIDs and global evaluation. No serious side effects were reported.
REVIEWER'S CONCLUSIONS: The evidence for avocado-soybean unsaponifiables in the treatment of osteoarthritis is convincing but evidence for the other herbal interventions is insufficient to either recommend or discourage their use.
补充和替代医学越来越受欢迎，这在慢性病患者中似乎尤为明显。在骨关节炎的治疗中，一种被认为可能有益的疗法是草药疗法（植物疗法）。
确定草药疗法治疗骨关节炎的有效性。
使用包括所有形式关节炎与草药相结合的术语，检索主流医学和补充医学数据库。我们检索了以下电子数据库：医学索引数据库（MEDLINE）、荷兰医学文摘数据库（EMBASE）、补充医学数据库（CISCOM）、联合和替代医学数据库（AMED）、护理学与健康领域数据库（CINAHL）、考克兰对照试验注册库（CCTR）、考克兰肌肉骨骼疾病专业注册库、论文摘要数据库、BIDS科学信息数据库和考克兰补充医学领域专业注册库。我们还检索了所检索试验的参考文献列表。
所有关于草药干预治疗骨关节炎的随机试验，与安慰剂进行比较。根据预先制定的方案以及两位独立阅读每篇入选论文以评估内容和质量的评审员之间的共识纳入研究。纳入任何语言的论文。
由同两位评审员独立提取数据。
五项研究（四种不同的草药干预）符合综述标准。两项研究适合进行数据合并。无法从单项研究中得出确凿结论，但两项关于鳄梨/大豆不皂化物的研究显示对功能指数、疼痛、非甾体抗炎药摄入量和总体评估有有益影响。未报告严重副作用。
鳄梨 - 大豆不皂化物治疗骨关节炎的证据令人信服，但其他草药干预的证据不足以推荐或不推荐使用。
