DR, DQ, and you: MHC alleles and autoimmunity.
作者信息
Sønderstrup G, McDevitt H O
机构信息
Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, California 94305-5124, USA.
出版信息
J Clin Invest. 2001 Apr;107(7):795-6. doi: 10.1172/JCI12634.
Abstract
摘要
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本文引用的文献
1
The regulatory role of DR4 in a spontaneous diabetes DQ8 transgenic model.DR4在自发性糖尿病DQ8转基因模型中的调节作用。
J Clin Invest. 2001 Apr;107(7):871-80. doi: 10.1172/JCI11708.
2
Co-expression of HLA DR3 and DQ8 results in the development of spontaneous insulitis and loss of tolerance to GAD65 in transgenic mice.HLA DR3和DQ8的共表达导致转基因小鼠发生自发性胰岛炎并丧失对谷氨酸脱羧酶65（GAD65）的耐受性。
Diabetes. 2000 Apr;49(4):548-54. doi: 10.2337/diabetes.49.4.548.
3
Complementation between specific HLA-DR and HLA-DQ genes in transgenic mice determines susceptibility to experimental autoimmune encephalomyelitis.转基因小鼠中特定HLA-DR和HLA-DQ基因之间的互补作用决定了对实验性自身免疫性脑脊髓炎的易感性。
Hum Immunol. 2000 Mar;61(3):279-89. doi: 10.1016/s0198-8859(99)00135-4.
4
HLA class II transgenic mice: models of the human CD4+ T-cell immune response.
Immunol Rev. 1999 Dec;172:335-43. doi: 10.1111/j.1600-065x.1999.tb01377.x.
5
In vivo evidence for the contribution of human histocompatibility leukocyte antigen (HLA)-DQ molecules to the development of diabetes.人类组织相容性白细胞抗原（HLA）-DQ分子对糖尿病发生作用的体内证据。
J Exp Med. 2000 Jan 3;191(1):97-104. doi: 10.1084/jem.191.1.97.
6
The role of MHC class II molecules in susceptibility and resistance to autoimmunity.MHC II类分子在自身免疫易感性和抗性中的作用。
Curr Opin Immunol. 1998 Dec;10(6):677-81. doi: 10.1016/s0952-7915(98)80088-5.
7
Modulation of HLA-DQ-restricted collagen-induced arthritis by HLA-DRB1 polymorphism.HLA-DRB1基因多态性对HLA-DQ限制的胶原诱导性关节炎的调节作用
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Identification of naturally processed T cell epitopes from glutamic acid decarboxylase presented in the context of HLA-DR alleles by T lymphocytes of recent onset IDDM patients.近期发病的胰岛素依赖型糖尿病患者的T淋巴细胞对在HLA-DR等位基因背景下呈递的谷氨酸脱羧酶天然加工的T细胞表位的鉴定。
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