Gilbert C, Foster A
Department of Epidemiology and International Eye Health, Institute of Ophthalmology, Bath Street, London EC1V 9EI, England.
Bull World Health Organ. 2001;79(3):227-32. Epub 2003 Jul 7.
The major causes of blindness in children vary widely from region to region, being largely determined by socioeconomic development, and the availability of primary health care and eye care services. In high-income countries, lesions of the optic nerve and higher visual pathways predominate as the cause of blindness, while corneal scarring from measles, vitamin A deficiency, the use of harmful traditional eye remedies, and ophthalmia neonatorum are the major causes in low-income countries. Retinopathy of prematurity is an important cause in middle-income countries. Other significant causes in all countries are cataract, congenital abnormalities, and hereditary retinal dystrophies. It is estimated that, in almost half of the children who are blind today, the underlying cause could have been prevented, or the eye condition treated to preserve vision or restore sight. The control of blindness in children is a priority within the World Health Organization's VISION 2020 programme. Strategies need to be region specific, based on activities to prevent blindness in the community--through measles immunization, health education, and control of vitamin A deficiency--and the provision of tertiary-level eye care facilities for conditions that require specialist management.
儿童失明的主要原因因地区而异,很大程度上取决于社会经济发展水平以及初级卫生保健和眼保健服务的可及性。在高收入国家,视神经和更高视觉通路的病变是失明的主要原因,而在低收入国家,麻疹导致的角膜瘢痕、维生素A缺乏、使用有害的传统眼药以及新生儿眼炎是主要原因。早产儿视网膜病变是中等收入国家的一个重要病因。在所有国家,其他重要病因包括白内障、先天性异常和遗传性视网膜营养不良。据估计,如今几乎一半失明儿童的潜在病因本可预防,或者其眼部疾病本可得到治疗以保住视力或恢复视力。儿童失明防治是世界卫生组织“视觉2020”计划的一项重点工作。需要根据社区预防失明的活动制定针对不同地区的策略,这些活动包括麻疹免疫接种、健康教育以及控制维生素A缺乏,同时还要为需要专科治疗的病症提供三级眼保健设施。