Oppermann H, Doering C, Sobottka A, Krämer U, Thriene B
Hygieneinstitut Sachsen-Anhalt, Magdeburg.
Gesundheitswesen. 2001 Feb;63(2):85-9. doi: 10.1055/s-2001-10962.
The interrelation between biological pollution of indoor spaces and health disorders, allergic symptoms and health issues in general is well known. Besides animal epithelia, the exposure to house dust mites and mould fungi is considered a serious risk factor. In the scope of a comparative study involving school beginners in East and West Germany (launched in 1991), dust was vacuumed from a total of 218 mattresses of children's beds and checked for their content of house dust mites and mould fungi. This investigation aimed at assessing the degree of exposure, to determine regional differences, if any, and to uncover the correlation between exposure and symptoms. Dust mite infestation was highest in the small town of Borken in Westphalia (in 86% of the specimens > 2 micrograms mite allergens/g of dust) and lowest in Magdeburg in Saxony-Anhalt (55.3%). Total concentrations of mould fungi varied from 1.4 x 10(3) CFU/g of dust and 300 x 10(3) CFU/g of dust with a geometric mean of 26.5 x 10(3) CFU/g of dust. A total of 41 different genera/species were identified. Most frequent were the following genera: Penicillium, Eurotium, Aspergillus, Alternaria, Epicoccum and Cladosporium. The importance of individual factors influencing was confirmed. Humidity decreases the higher the flat is situated in a building. This partly explains the differences in concentrations between Borken where children live mainly on the ground floor, and the other cities with taller buildings. Spores of mould fungi were discovered more frequently in mattresses from humid flats. An association between biological indoor space factors and some allergological parameters seemed obvious, however, due to the small size of the test group most of them were not significant.
室内空间的生物污染与健康问题、过敏症状及总体健康问题之间的相互关系是众所周知的。除了动物上皮外，接触屋尘螨和霉菌被认为是一个严重的风险因素。在一项涉及东德和西德学童（始于1991年）的比较研究范围内，从儿童床的218个床垫上吸尘，并检查其中屋尘螨和霉菌的含量。这项调查旨在评估接触程度，确定是否存在区域差异，并揭示接触与症状之间的相关性。屋尘螨感染率在威斯特法伦州的博尔肯小镇最高（在所有样本中，86%的样本螨过敏原含量>2微克/克灰尘），在萨克森-安哈尔特州的马格德堡最低（55.3%）。霉菌的总浓度在1.4×10³CFU/克灰尘至300×10³CFU/克灰尘之间变化，几何平均值为26.5×10³CFU/克灰尘。共鉴定出41个不同的属/种。最常见的属如下：青霉属、散囊菌属、曲霉属、链格孢属、附球菌属和枝孢属。影响因素的重要性得到了证实。楼层越高，湿度越低。这部分解释了博尔肯（儿童主要住在底层）与其他高楼林立城市之间浓度差异的原因。在潮湿公寓的床垫中更频繁地发现霉菌孢子。室内生物空间因素与一些过敏参数之间的关联似乎很明显，然而，由于测试组规模较小，其中大多数关联并不显著。
