Abdel-Aziz S A, Anderson W
J Pharm Pharmacol. 1976 Nov;28(11):801-5. doi: 10.1111/j.2042-7158.1976.tb04060.x.
Decrease in the solvation of polymer by inclusion of ethanol in the acetone casting solution resulted in greater permeability to urea of cast acrylate-methacrylate film. The greater permeability was accompanied particularly by a decrease in pore size and increase in pore number, despite the absence of change in pore area. A decrease in cohesiveness in the film was suggested by the decrease in tortuosity of the pores as seen by scanning electron microscopy; also, water uptake was increased when the film was cast from an ethanolic solution. The results support the view that, in practice, the composition of the solvent, by its effect on microstructure, can affect the function of the film cast from it.
在丙酮浇铸溶液中加入乙醇会降低聚合物的溶剂化作用，从而使浇铸的丙烯酸酯 - 甲基丙烯酸酯薄膜对尿素的渗透性增强。尽管孔隙面积没有变化，但渗透性增强尤其伴随着孔径减小和孔隙数量增加。扫描电子显微镜观察到孔隙曲折度降低，这表明薄膜内聚力下降；此外，从乙醇溶液浇铸薄膜时，吸水率增加。这些结果支持了这样一种观点，即在实际应用中，溶剂的组成通过对微观结构的影响，能够影响由其浇铸而成薄膜的功能。
