Okor R S, Anderson W
J Pharm Pharmacol. 1987 Jul;39(7):547-8. doi: 10.1111/j.2042-7158.1987.tb03174.x.
Films of certain acrylate-methacrylate copolymers of varying cation (quaternary ammonium) content were cast from three different solvents: acetone, chloroform, and ethanol; their permeability to urea was determined at 30 degrees C. In films containing 66 mole cation mol-1 polymer chain, and cast from acetone, chloroform or ethanol, the permeation rates were 480,900 and 2807 mg h-1, respectively. Differences in permeation rates were however less significant when polymers of cation content lower than 46 mole cation mol-1 polymer chain were used to form films. This observation may relate to differences in the degree of dissociation of the polymer in the different solvents.
由三种不同溶剂（丙酮、氯仿和乙醇）浇铸制备了具有不同阳离子（季铵）含量的某些丙烯酸酯 - 甲基丙烯酸酯共聚物薄膜；在30℃下测定了它们对尿素的渗透性。对于含66摩尔阳离子/摩尔聚合物链且由丙酮、氯仿或乙醇浇铸而成的薄膜，其渗透速率分别为480、900和2807 mg h⁻¹。然而，当使用阳离子含量低于46摩尔阳离子/摩尔聚合物链的聚合物来形成薄膜时，渗透速率的差异不太显著。这一观察结果可能与聚合物在不同溶剂中的解离程度差异有关。
