This report presents the recommendations of a WHO Expert Committee responsible for updating and revising the Model List of Essential Drugs. The first part describes the criteria for the selection of essential drugs and pharmaceutical dosage forms, and includes discussion of quality assurance, pharmacovigilance, drug utilization studies, drug information and educational activities, and future developments of the model list. In the light of increasing resistance to antimicrobials, particular attention is drawn to the need for and use of reserve antimicrobials. The second part presents the eleventh revised model list, together with details of the changes that have been made, a glossary of terms and an alphabetical index of all the drugs included.
本报告介绍了负责更新和修订基本药物示范目录的世界卫生组织专家委员会的建议。第一部分描述了基本药物和药物剂型的选择标准,包括对质量保证、药物警戒、药物利用研究、药物信息和教育活动以及示范目录未来发展的讨论。鉴于对抗微生物药物的耐药性不断增加,特别提请注意储备抗微生物药物的必要性和使用情况。第二部分列出了第十一次修订的示范目录,以及所做更改的详细信息、术语表和所有列入药物的字母索引。