Adams J M, Cory S
Nature. 1975 May 1;255(5503):28-33. doi: 10.1038/255028a0.
Messenger RNAs from mouse myeloma cells contain N-6-methyl adenosine and novel 5' termini having 7-methy-guanosine in a 5', 5' triphosphate linkage with ribose-methylated nucleosides. Ten common 5'-terminal sequences of the forms m-7-G-5'-PPP-5'-NmpNp and m-7-G-5'-ppp-5'-NmpNmpNp are reported. Structures like this may be a general feature of mRNA in eukaryotes.
来自小鼠骨髓瘤细胞的信使核糖核酸含有N-6-甲基腺苷以及具有7-甲基鸟苷的新型5'末端，该末端通过5',5'-三磷酸键与核糖甲基化核苷相连。报道了十种常见的5'-末端序列，形式为m-7-G-5'-PPP-5'-NmpNp和m-7-G-5'-ppp-5'-NmpNmpNp。这样的结构可能是真核生物中mRNA的一个普遍特征。
