Bogaerts J, Ahmed J, Akhter N, Begum N, Rahman M, Nahar S, Van Ranst M, Verhaegen J
Laboratory Sciences Division, ICDDR,B, Dhaka, Bangladesh.
Sex Transm Infect. 2001 Apr;77(2):114-9. doi: 10.1136/sti.77.2.114.
To document the prevalence of reproductive tract infections (RTI) and sexually transmitted infections (STI) among women attending a basic healthcare clinic in Dhaka, Bangladesh, to identify risk factors associated with the diseases and to estimate the incidence of syphilis, hepatitis C (HCV), hepatitis B (HBV), and herpes simplex type 2 (HSV-2) infection.
A cross sectional sample of 2335 consecutive women was examined during 1996-8. Women were interviewed about risk factors for RTI/STI and tested for Neisseria gonorrhoeae, Chlamydia trachomatis, Trichomonas vaginalis, Treponema pallidum, HIV, HCV, HBV, HSV-1 and HSV-2 infection as well as vaginal candidosis and bacterial vaginosis. Women with antibodies to T pallidum were retested at regular intervals. One year after ending the study seroconversion for syphilis, HBV, HCV, and HSV-2 infection was detected among women initially negative for the respective diseases.
The overall prevalence rate of N gonorrhoeae, C trachomatis, T vaginalis, and T pallidum infection was 0.5%, 1.9%, 2.0%, and 2.9% respectively. Overall, 35% of the women had antibodies to hepatitis B core antigen, 0.9% had HCV, and 12% HSV-2 infection. Risk factors for gonorrhoea/C trachomatis infection were a husband not living at home or suspected of being unfaithful. HSV-2 infection was associated with the same risk factors and with a polygamous marriage. The prevalence of HSV-2 infection among women "at risk" was 23%. HIV infection was not diagnosed. Repeated serological examination indicated that only 32% of women with serological evidence of syphilis had active disease. The seroincidences of HBV, HCV, and HSV-2 were 0.03, 0.007, and 0.009 per person year. Seroconversion for syphilis was not observed.
记录孟加拉国达卡一家基层医疗诊所就诊女性的生殖道感染（RTI）和性传播感染（STI）患病率，确定与这些疾病相关的危险因素，并估计梅毒、丙型肝炎（HCV）、乙型肝炎（HBV）和2型单纯疱疹病毒（HSV-2）感染的发病率。
在1996年至1998年期间，对2335名连续就诊的女性进行了横断面抽样检查。就RTI/STI的危险因素对女性进行了访谈，并检测了淋病奈瑟菌、沙眼衣原体、阴道毛滴虫、梅毒螺旋体、人类免疫缺陷病毒（HIV）、HCV、HBV、1型单纯疱疹病毒（HSV-1）和HSV-2感染以及阴道念珠菌病和细菌性阴道病。对梅毒螺旋体抗体阳性的女性定期进行复查。在研究结束一年后，在最初对相应疾病检测为阴性的女性中检测到梅毒、HBV、HCV和HSV-2感染的血清学转换。
淋病奈瑟菌、沙眼衣原体、阴道毛滴虫和梅毒螺旋体感染的总体患病率分别为0.5%、1.9%、2.0%和2.9%。总体而言，35%的女性有乙型肝炎核心抗原抗体，0.9%有HCV感染，12%有HSV-2感染。淋病/沙眼衣原体感染的危险因素是丈夫不住在家或被怀疑不忠。HSV-2感染与相同的危险因素以及一夫多妻制婚姻有关。“高危”女性中HSV-2感染的患病率为23%。未诊断出HIV感染。重复血清学检查表明，仅有血清学证据证明感染梅毒的女性中，只有32%患有活动性疾病。HBV、HCV和HSV-2的血清发病率分别为每人每年0.03、0.007和0.009例。未观察到梅毒的血清学转换。
