Johnston I H, Duff J, Jacobson E E, Fagan E
Royal Alexandra Hospital for Children, Westmead, Australia.
Pediatr Neurosurg. 2001 Feb;34(2):63-72. doi: 10.1159/000055997.
Twelve patients are described who were found to have asymptomatic intracranial hypertension monitored over an extended (6 months to 6 years) period. There were three groups: 5 patients with treated hydrocephalus with an apparently functioning shunt, 4 patients with untreated hydrocephalus, clinically and radiologically nonprogressive, and 3 patients with pseudotumor cerebri, 2 treated and 1 untreated. Although the magnitude of the intracranial pressure changes varied, all patients had abnormal baseline pressures together with repeated A and B waves. In no case was there any clinical manifestation of raised intracranial pressure and in all cases ventricular size remained constant over the period of evaluation. The clinical and pathophysiological implications of these findings are discussed.
本文描述了12例患者，这些患者在长达6个月至6年的时间内被监测出患有无症状颅内高压。分为三组：5例接受治疗的脑积水患者，分流器功能明显正常；4例未治疗的脑积水患者，临床和影像学检查显示病情无进展；3例假性脑瘤患者，2例接受治疗，1例未治疗。尽管颅内压变化的幅度各不相同，但所有患者的基线压力均异常，且反复出现A波和B波。在评估期间，所有患者均未出现颅内压升高的临床表现，脑室大小均保持不变。本文讨论了这些发现的临床和病理生理学意义。
