Krakhmal'nikova G Kh, Bukhman A I, Zarubina N A, Gracheva L I, Lomovitskaia T S
Probl Endokrinol (Mosk). 1975 Mar-Apr;21(2):41-5.
The authors present clinical and roentgenological characteristics of toxoplasmosis revealed in 46 of 128 patients with neuro-endocrine form of diencephalic syndrome, cerebro-hypophyseal nanism and hypogenitalism, examined for toxoplasmosis. Congenital toxoplasmosis was found in 29 and chronic acquired--in 17 cases. It was noted that the clinical picture of both the congenital and of the chronic acquired toxoplasmosis in patients with endocrine diseases was varied due to affection of different organs and systems of the organism. Of great significance in the complex clinico-laboratory diagnosis of congenital and chronic acquired toxoplasmosis was the roentgenological method of study. Roentgenological changes in the skull of the patients with endocrine diseases and toxoplasmosis were expressed in the presence of calcifications of various shape and size (from 2 mm to 2 cm), calcification of the dura mater in the frontal portion and the area of the sella turcica, and hyperostosis. Diagnosis of congenital and chronic acquired toxoplasmosis in patients with endocrine disturbances should be based on the results of complex clinico-roentgenological and laboratory studies.
作者介绍了128例接受弓形虫病检查的患有神经内分泌型间脑综合征、脑垂体性侏儒症和生殖腺功能减退症患者中46例所表现出的弓形虫病的临床和放射学特征。先天性弓形虫病29例,慢性获得性弓形虫病17例。值得注意的是,由于机体不同器官和系统受到影响,内分泌疾病患者的先天性和慢性获得性弓形虫病的临床表现各不相同。放射学研究方法在先天性和慢性获得性弓形虫病的综合临床实验室诊断中具有重要意义。内分泌疾病合并弓形虫病患者颅骨的放射学改变表现为存在各种形状和大小(从2毫米到2厘米)的钙化、额部和蝶鞍区域硬脑膜钙化以及骨质增生。对内分泌紊乱患者先天性和慢性获得性弓形虫病的诊断应基于综合临床放射学和实验室研究结果。