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溴吡斯的明与女性后备役海湾战争退伍军人样本的长期主观健康状况:简要报告

Pyridostigmine bromide and the long-term subjective health status of a sample of female reserve component Gulf War veterans: a brief report.

作者信息

Schumm W R, Reppert E J, Jurich A P, Bollman S R, Castelo C, Sanders D, Webb F J

机构信息

School of Family Studies and Human Services, Justin 343K, Kansas State University, 1700 Anderson Avenue, Manhattan, KS 66506-1403, USA.

出版信息

Psychol Rep. 2001 Feb;88(1):306-8. doi: 10.2466/pr0.2001.88.1.306.

DOI:10.2466/pr0.2001.88.1.306
PMID:11293048
Abstract

The role of pyridostigmine bromide (PB) pills in explaining the long-term subjective health status of a sample of over 100 female Reserve Component Gulf War veterans was examined through regression analysis. Results fell just short of significance (p < .06) for the prediction of subjective health approximately six years after the war and were clearly not significant for the prediction of subjective health at previous times. Results parallel Golomb's 1999 RAND report, which found suggestive but not conclusive evidence for the possible adverse effects of Gulf War veterans' consumption of pyridostigmine bromide pills. Our data suggest that use of more than 10 pills may have been especially risky with respect to long-term subjective health.

摘要

通过回归分析,研究了溴吡斯的明(PB)片在解释100多名女性后备役海湾战争退伍军人样本的长期主观健康状况方面的作用。对于战后约六年的主观健康预测,结果略低于显著性水平(p < 0.06),而对于之前各时期的主观健康预测,结果显然不显著。这些结果与戈洛姆1999年的兰德报告相似,该报告发现了海湾战争退伍军人服用溴吡斯的明片可能产生的不良影响的暗示性但非决定性证据。我们的数据表明,就长期主观健康而言,服用超过10片药物可能尤其危险。

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Pyridostigmine bromide and the long-term subjective health status of a sample of female reserve component Gulf War veterans: a brief report.溴吡斯的明与女性后备役海湾战争退伍军人样本的长期主观健康状况:简要报告
Psychol Rep. 2001 Feb;88(1):306-8. doi: 10.2466/pr0.2001.88.1.306.
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Neuropharmacology. 2020 Jul;171:108073. doi: 10.1016/j.neuropharm.2020.108073. Epub 2020 Apr 2.
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Acetylcholinesterase inhibitors and Gulf War illnesses.乙酰胆碱酯酶抑制剂与海湾战争疾病
Proc Natl Acad Sci U S A. 2008 Mar 18;105(11):4295-300. doi: 10.1073/pnas.0711986105. Epub 2008 Mar 10.