Janeczko D, Kopczyński J, Lewandowski Z, Janeczko-Sosnowska E, Tuszyńska A
Katedra i Klinika Gastroenterologii i Chorób Przemiany Materii Akademii Medycznej w Warszawie.
Przegl Lek. 2000;57 Suppl 4:3-7.
In the period 1973/74-1995 a prospective observation was carried out on 4420 diabetic patients (1990 males and 2430 females) aged 30-68 years, with type 2 (non-insulin dependent diabetes) of 1-10 years duration. During the 22-year period nearly 80% of the initial cohort died. The risk of death was 2-times higher in diabetes than in the samples of general population observed at the same time. The death risk from cardiovascular diseases was over 3.0 times higher than in general population. The relevant risk ratio was found over 5-times higher for coronary heart disease, which was unlike to result from the differences in death ascertainment between diabetics and the city dwellers. The all-causes ratio of death and cardiovascular diseases was the same for women and men but it was selectively higher for females than males group for coronary heart disease and cerebrovascular diseases, and for males 50% higher for atherosclerosis and other heart diseases. The highest cumulation of risk factors was observed for deaths from cardiovascular diseases, and coronary heart disease. There were risk factors typical for cardiovascular disease and typical for poor metabolic control of diabetes (hyperglycaemia, glucosuria) and presence of complications of diabetes (nephropathy).
在1973/74年至1995年期间，对4420名年龄在30至68岁之间、患有病程为1至10年的2型（非胰岛素依赖型糖尿病）糖尿病患者（1990名男性和2430名女性）进行了前瞻性观察。在这22年期间，近80%的初始队列患者死亡。糖尿病患者的死亡风险比同时观察的普通人群样本高2倍。心血管疾病导致的死亡风险比普通人群高3.0倍以上。冠心病的相关风险比高出5倍多，这不太可能是由于糖尿病患者与城市居民在死亡确定方面的差异所致。全因死亡和心血管疾病的比例在男性和女性中相同，但冠心病和脑血管疾病在女性组中的选择性死亡率高于男性组，而动脉粥样硬化和其他心脏病在男性中的死亡率比女性高50%。心血管疾病和冠心病死亡的风险因素累积最高。存在心血管疾病典型的风险因素以及糖尿病代谢控制不佳（高血糖、糖尿）和糖尿病并发症（肾病）的典型风险因素。
