Arnold J, Pinsky S, Ryo U Y, Frohman L, Schneider A, Favus M, Stachura M, Arnold M, Colman M
Radiology. 1975 Jun;115(3):653-7. doi: 10.1148/15.3.653.
Histories, physical examinations and 99mTc-pertechnetate imaging were used to evaluate 1,452 persons who had had x-ray therapy to the neck region for benign conditions 18 to 35 years previously. Thyroid abnormalities were found in 301 patients (21%) and thyroid malignancy was found in 29% of 193 patients with abnormal studies who were explored surgically. Thyroid imaging detected 96% of these abnormalities, 40% of which would not have been unequivocally established by physical examination alone. Nuclear imaging could not distinguish benign from malignant lesions.
对1452名18至35年前因良性疾病接受颈部X线治疗的患者进行了病史、体格检查及99m锝高锝酸盐显像评估。301例患者（21%）发现甲状腺异常，在193例接受手术探查的检查异常患者中，29%发现甲状腺恶性肿瘤。甲状腺显像检测出这些异常中的96%，其中40%仅通过体格检查无法明确诊断。核成像无法区分良性和恶性病变。
