Valdiserri R O, Borochovitz D
Arch Pathol Lab Med. 1980 Mar;104(3):150-2.
Thyroid tissue from 90 patients with a history of therapeutic irradiation to the head and neck in childhood and adolescence was examined microscopically. In addition to the well-known observation that these individuals have an increased incidence of primary thyroid carcinoma, it was also demonstrated that they have an increased incidence of benign histologic changes. These changes represent a spectrum from nonspecific hyperplastic lesions to benign neoplasia and thyroiditis.
对90例童年和青春期曾接受头颈部治疗性放射治疗的患者的甲状腺组织进行了显微镜检查。除了这些个体原发性甲状腺癌发病率增加这一众所周知的观察结果外，还证实他们良性组织学改变的发病率也增加。这些改变代表了一个从非特异性增生性病变到良性肿瘤和甲状腺炎的谱系。
