Riba J, Rodríguez-Fornells A, Strassman R J, Barbanoj M J
Area d'Investigació Farmacològica, Institut de Recerca, Hospital de Sant Pau (HSCSP), Sant Antoni M. Claret, 167, 08025 Barcelona, Spain.
Drug Alcohol Depend. 2001 May 1;62(3):215-23. doi: 10.1016/s0376-8716(00)00175-7.
Reliability and convergent-discriminant validity of a Spanish version of the Hallucinogen Rating Scale (HRS) were assessed in two differentiated populations of hallucinogen users involving the retrospective assessment of drug effects. In Study 1 (immediate assessment), 75 European users of the South American hallucinogenic drink ayahuasca answered the HRS 4 h after drug intake in their habitual setting. In Study 2 (delayed assessment), 56 adult polydrug users answered the HRS and a short form of the Addiction Research Center Inventory (ARCI) recalling the effects they experienced when they last took a hallucinogen, in order to test the convergent-discriminant validity of HRS with the scales of the standard questionnaire used in most studies involving psychoactive drugs. The HRS scales showed increases after both the immediate and delayed retrospective assessment of drug effects. Reliability data indicated that four of the six scales show an acceptable level of internal consistency. Significant but limited correlations were found between the Perception and Somaesthesia scales and the ARCI LSD scale, pointing out the questionnaire's construct validity. Thus, the HRS was sensitive to hallucinogenic drug effects other than those elicited by intravenous N,N-dimethyltryptamine (DMT), for which it was originally designed, and showed reasonable reliability and convergent validity. Results suggest its usefulness in the evaluation of subjective effects elicited by psychoactive drugs with hallucinogenic properties, and constitute a preliminary approach to the effects of ayahuasca in European subjects.
在两个不同的致幻剂使用者群体中,对西班牙语版致幻剂评定量表(HRS)的信度和聚合区分效度进行了评估,涉及对药物效果的回顾性评估。在研究1(即时评估)中,75名使用南美致幻饮料死藤水的欧洲使用者在其惯常环境中服药4小时后回答了HRS。在研究2(延迟评估)中,56名成年多药使用者回答了HRS和成瘾研究中心量表简版(ARCI),回忆他们上次服用致幻剂时所经历的效果,以检验HRS与大多数涉及精神活性药物研究中使用的标准问卷量表的聚合区分效度。HRS量表在药物效果的即时和延迟回顾性评估后均有所增加。信度数据表明,六个量表中的四个显示出可接受的内部一致性水平。在感知和躯体感觉量表与ARCI麦角酸二乙胺(LSD)量表之间发现了显著但有限的相关性,表明了该问卷的结构效度。因此,HRS对除其最初设计用于评估的静脉注射N,N - 二甲基色胺(DMT)所引发的致幻药物效果之外的其他效果敏感,并显示出合理的信度和聚合效度。结果表明其在评估具有致幻特性的精神活性药物引发的主观效果方面有用,并构成了对欧洲受试者中死藤水效果的初步研究。