Thiemann W H, Meierhenrich U
University of Bremen, Department of Physical Chemistry, NW II, FB 02, Leobener Strasse, D-28359 Bremen, Germany.
Orig Life Evol Biosph. 2001 Feb-Apr;31(1-2):199-210. doi: 10.1023/a:1006718920805.
New crucial theoretical investigations on the origin of biomolecular chirality are reviewed briefly. With the goal to investigate these theories our team is going to perform the 'chirality-experiment' in the near future with cometary matter. In 2012 the robotical lander RoLand will detach from the orbiter of the ROSETTA spacecraft and set down on the surface of comet 46P/Wirtanen in order to separate and identify cometary organic compounds via GC-MS in situ. Chiral organics will be separated into their enantiomers by application of 3 capillary columns coated with different kinds of stationary phases. Non-volatile compounds like amino acids will be derivatized in especially developed gas phase alkylation steps avoiding reactions in the liquid phase. The results of these preliminary gas phase reactions are presented in this article.
简要回顾了关于生物分子手性起源的新的重要理论研究。为了研究这些理论，我们的团队计划在不久的将来用彗星物质进行“手性实验”。2012年，机器人着陆器RoLand将从罗塞塔号航天器的轨道器上分离，降落在46P/维尔特南彗星的表面，以便通过气相色谱 - 质谱联用仪原位分离和识别彗星有机化合物。手性有机物将通过应用三根涂有不同固定相的毛细管柱分离成其对映体。像氨基酸这样的非挥发性化合物将在特别开发的气相烷基化步骤中进行衍生化，避免在液相中发生反应。本文展示了这些初步气相反应的结果。
