关于洛杉矶（LA）与组织相容性抗原A（HL - A）系统四个位点之间连锁估计的异质性

On the heterogeneity of linkage estimations between LA and four loci of the HL-A system,

作者信息

Belvedere M C, Curtoni E S, Dausset J, Lamm L U, Mayr W, van Rood J J, Svejgaard A, Piazza A

出版信息

Tissue Antigens. 1975 Apr;5(2):99-102. doi: 10.1111/j.1399-0039.1975.tb00536.x.

DOI:10.1111/j.1399-0039.1975.tb00536.x

Abstract

Three cases of crossing over between the LA and FOUR loci of HL-A system are presented in this note. Recombination fractions between those two loci are also calculated from familial data kindly provided by other European laboratories. It is suggested that differences found in maternal and paternal recombination frequency are due to the heterogeneity of estimates of each laboratory.

摘要

本文报告了3例HL - A系统中LA与FOUR位点之间发生交换的病例。还根据其他欧洲实验室提供的家族数据计算了这两个位点之间的重组率。结果表明，所发现的母系和父系重组频率的差异是由于每个实验室估计值的异质性所致。