Yman L
Pharmacia Diagnostics AB, Uppsala, Sweden.
Allergy. 2001;56 Suppl 67:70-4. doi: 10.1111/j.1398-9995.2001.00921.x.
IgE-antibody analysis is a major diagnostic procedure and a primary tool in allergological research. The determination of sensitization frequencies and antibody concentrations against allergens of defined sources provides critical information for the estimation of the relative importance of food and environment in clinical allergy. True quantitation is essential and requires assay designs providing allergen excess and mass unit calibration. Standardized and reproducible methods show geographic and culture dependent differences between patient populations and contribute to the quality of diagnosis and treatment of allergic disease.
IgE 抗体分析是一项主要的诊断程序，也是过敏学研究的主要工具。确定针对特定来源过敏原的致敏频率和抗体浓度，可为评估食物和环境在临床过敏中的相对重要性提供关键信息。真正的定量至关重要，需要提供过敏原过量和质量单位校准的检测设计。标准化且可重复的方法显示出不同患者群体之间存在地域和文化依赖性差异，有助于提高过敏性疾病的诊断和治疗质量。
