Xu X, Low D W, Palevsky H I, Elenitsas R
Department of Pathology and Laboratory Medicine, Hospital of University of Pennsylvania, 6 Founfer's Building, 3400 Spruce St., Philadelphia, PA 19104, USA.
Dermatol Surg. 2001 Apr;27(4):343-6. doi: 10.1046/j.1524-4725.2001.00308.x.
Phaeohyphomycosis is a skin fungal infection caused by dematiaceous fungi that often affects immunocompromised patients. Local recurrence after medication or surgical treatment is common in these patients. We present a case in which a 42-year-old woman status post-bilateral lung transplant developed phaeohyphomycotic cysts with local recurrence and then was successfully treated by local excision with pre- and postsurgery oral itraconazole treatment.
To demonstrate the utility of pre- and postsurgery oral itraconazole in immunocompromised patients with recurrent phaeohyphomycosis.
Local excision with pre- and postsurgery oral itraconazole treatment.
Simple excision or excision with postsurgery oral itraconazole resulted in local recurrence in this patient. Local excision with pre- and postsurgery oral itraconazole was effective in preventing the local recurrence.
Phaeohyphomycosis can run a prolonged course in immunocompromised patients with multiple recurrences. Local excision with pre- and postsurgery oral itraconazole can be used to treat these patients with recurrent phaeohyphomycosis.
暗色丝孢霉病是一种由暗色真菌引起的皮肤真菌感染，常影响免疫功能低下的患者。这些患者在药物治疗或手术治疗后局部复发很常见。我们报告一例42岁双侧肺移植术后女性发生暗色丝孢霉囊肿并局部复发，随后通过局部切除并在术前和术后口服伊曲康唑成功治疗的病例。
证明术前和术后口服伊曲康唑在免疫功能低下的复发性暗色丝孢霉病患者中的作用。
局部切除并在术前和术后口服伊曲康唑治疗。
单纯切除或术后口服伊曲康唑切除导致该患者局部复发。术前和术后口服伊曲康唑的局部切除有效预防了局部复发。
暗色丝孢霉病在免疫功能低下且多次复发的患者中病程可能延长。术前和术后口服伊曲康唑的局部切除可用于治疗这些复发性暗色丝孢霉病患者。
