Van Herwaarden M A, Samsom M, Akkermans L M, Smout A J
Gastrointestinal Research Unit, Department of Gastroenterology, University Medical Center Utrecht, The Netherlands.
Neurogastroenterol Motil. 2001 Apr;13(2):111-9. doi: 10.1046/j.1365-2982.2001.00253.x.
The aim of our study was to investigate the recording fidelity of a water-perfused micromanometric catheter with incorporated sleeve combined with a newly developed portable water-perfused manometric system for pharyngeal, oesophageal and lower oesophageal sphincter (LOS) pressure recording. The system's performance was assessed in prolonged recordings in ambulant gastro-oesophageal reflux disease (GORD) patients. Eighty 24-h studies in GORD patients, carried out with the perfused portable manometric system, were evaluated. Twelve of these recordings were analysed in detail in order to compare oesophageal and LOS motor patterns with those described previously. Paired 2-h manometric recordings of the pharynx, oesophagus, LOS and stomach, using the new system and a conventional perfused stationary manometric system, were performed in eight healthy subjects. With the portable manometric system oesophageal contractions, transient LOS relaxations, swallow-associated prolonged LOS relaxations and LOS pressures were recorded with equal fidelity to the conventional manometric system. Recordings obtained with the portable system showed meal-related and diurnal variations in oesophageal and LOS variables that were similar to these found in studies using conventional equipment. The new manometric system, consisting of a perfused micromanometric catheter with incorporated sleeve and a portable perfusion system, enables prolonged studies on oesophageal and LOS motor patterns in ambulant subjects.
我们研究的目的是调查一种带有内置套管的水灌注微测压导管与新开发的便携式水灌注测压系统相结合用于记录咽、食管和食管下括约肌（LOS）压力的记录保真度。在动态胃食管反流病（GORD）患者的长时间记录中评估了该系统的性能。对使用灌注便携式测压系统对GORD患者进行的80项24小时研究进行了评估。对其中12项记录进行了详细分析，以便将食管和LOS运动模式与先前描述的模式进行比较。在8名健康受试者中，使用新系统和传统的灌注固定式测压系统对咽、食管、LOS和胃进行了配对的2小时测压记录。使用便携式测压系统记录食管收缩、LOS短暂松弛、吞咽相关的LOS长时间松弛和LOS压力的保真度与传统测压系统相同。使用便携式系统获得的记录显示，食管和LOS变量存在与进餐相关和昼夜变化，这与使用传统设备的研究中发现的情况相似。由带有内置套管的灌注微测压导管和便携式灌注系统组成的新测压系统，能够对动态受试者的食管和LOS运动模式进行长时间研究。
