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[脑图谱与注意力缺陷多动障碍]

[Cerebral mapping and attention-deficit hyperactivity syndrome].

作者信息

Valdizán Usón J R, Navascués Sanagustín M A, Sebastián Guerrero M V

机构信息

Dpto. Matemática Aplicada; C.P.S. de Ingenieros, Zaragoza, España.

出版信息

Rev Neurol. 2001;32(2):127-32.

Abstract

INTRODUCTION

The clinical features of the attention-deficit hyperactivity disorder are characterized by attention deficit, an impulsive style of behavior and cognition and excessive motor activity. The incidence is estimated to be between 3 and 5% of the school population, and it is considered that there are one or two children with attention deficit in all children s classes during the early years of schooling.

OBJECTIVE

Electroencephalogram measurements using spectral analysis gives fresh information about the cerebral electrogenesis of children with attention-deficit hyperactivity disorder.

PATIENTS AND METHODS

In this study we diagnosed 21 children as having attention-deficit hyperactivity disorder and compared them with a control group of 13 healthy children of the same average age, at rest and whilst carrying out various tasks.

RESULTS AND CONCLUSIONS

Greater values of delta relative amplitude were found in the attention-deficit hyperactivity disorder group in their basal EEG at the F7, F8, FP1, FP2, F3, F4 and C3 sites. During visual testing differences were observed in the alpha band, also in the frontal region (F7, FP1, FP2 and F4) with the children of the control group showing the higher values. The level of significance used was 0.05. The cortical distribution of the dominant frequencies was different also. In addition, we present a method for cerebral mapping by means of spline functions developed by Duchon, which allow cerebral bioelectrical activity to be mapped in three dimensions.

摘要

引言

注意力缺陷多动障碍的临床特征表现为注意力不集中、行为和认知的冲动风格以及过度的运动活动。据估计,其发病率在在校学生中为3%至5%,并且人们认为在入学早期的所有班级中,每班级有一两个患有注意力缺陷的儿童。

目的

使用频谱分析进行脑电图测量可为注意力缺陷多动障碍儿童的脑电发生提供新信息。

患者与方法

在本研究中,我们诊断出21名儿童患有注意力缺陷多动障碍,并将他们与13名平均年龄相同的健康儿童组成的对照组进行比较,分别在静息状态和执行各种任务时进行观察。

结果与结论

在注意力缺陷多动障碍组的基础脑电图中,在F7、F8、FP1、FP2、F3、F4和C3部位发现δ相对波幅的值更高。在视觉测试期间,在α波段也观察到差异,同样在额叶区域(F7、FP1、FP2和F4),对照组儿童的值更高。使用的显著性水平为0.05。优势频率的皮层分布也有所不同。此外,我们提出了一种通过杜雄开发的样条函数进行脑图谱绘制的方法,该方法可将脑生物电活动进行三维映射。

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