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私人医生为阿片类药物成瘾者开具美沙酮处方的情况:与英格兰东南部国民保健服务体系的做法比较。

Methadone prescribing to opiate addicts by private doctors: comparison with NHS practice in south east England.

作者信息

Strang J, Sheridan J

机构信息

The National Addiction Centre (Institute of Psychiatry/Maudsley), London, UK.

出版信息

Addiction. 2001 Apr;96(4):567-76. doi: 10.1080/09652140020031610.

Abstract

AIMS

To compare National Health Service (NHS) and private practice in prescribing methadone to opiate addicts.

DESIGN AND PARTICIPANTS

Survey of community pharmacies during 1995 (one in four random sample) and during 1997 (one in two random sample) in which data were collected on all methadone prescriptions currently being dispensed to opiate addicts.

SETTING

Dispensing community pharmacies in south east England. UNITS MEASURED: 829 methadone prescriptions (785 NHS and 44 private) from 1995, and 761 (703 NHS and 58 private) from 1997.

MEASUREMENTS

(i) The prescribed daily dose of methadone; (ii) the form (oral mixture, tablets or ampoules); and (iii) the pick-up duration (daily collection of prescribed dose, through to weekly or fortnightly collection in a single pick-up).

FINDINGS

Private methadone prescriptions issued to addicts typically give twice the daily dose, are more than four times as likely to give the methadone in injectable form, and most commonly give prescriptions to be collected in a single large weekly or fortnightly installment instead of through daily dispensing, compared with NHS methadone prescriptions.

CONCLUSIONS

The disparity between private and NHS methadone prescriptions is striking. The much higher doses, the lack of arrangements for installment collection and the frequent choice of injectable forms of methadone increase greatly the risk of abuse and diversion to the black market. Regulatory scrutiny of this private practice in the United Kingdom is currently minimal. Independent research is required to explore more fully the different nature of such private methadone prescribing.

摘要

目的

比较国民保健制度(NHS)和私人诊所为阿片类成瘾者开具美沙酮处方的情况。

设计与参与者

对1995年(四分之一随机样本)和1997年(二分之一随机样本)的社区药房进行调查,收集所有当前正在为阿片类成瘾者配药的美沙酮处方数据。

地点

英格兰东南部的配药社区药房。测量单位:1995年的829份美沙酮处方(785份NHS处方和44份私人处方),以及1997年的761份(703份NHS处方和58份私人处方)。

测量指标

(i)美沙酮的每日处方剂量;(ii)剂型(口服混合剂、片剂或安瓿剂);(iii)取药时长(从每日领取处方剂量,到单次领取的每周或每两周领取)。

研究结果

与NHS美沙酮处方相比,开具给成瘾者的私人美沙酮处方通常每日剂量是其两倍,开具注射剂型美沙酮的可能性是其四倍多,并且最常见的是开具处方让患者每周或每两周一次性大量领取,而非每日配药。

结论

私人美沙酮处方与NHS美沙酮处方之间的差异显著。高得多的剂量、缺乏分期取药安排以及频繁选择注射剂型的美沙酮,大大增加了滥用和流入黑市的风险。目前英国对这种私人诊所的监管审查极少。需要进行独立研究,以更全面地探究这种私人美沙酮处方的不同性质。

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