Abel T, Lattal K M
Department of Biology, University of Pennsylvania, 3740 Hamilton Walk, Philadelphia, PA 19104, USA.
Curr Opin Neurobiol. 2001 Apr;11(2):180-7. doi: 10.1016/s0959-4388(00)00194-x.
Memory is often considered to be a process that has several stages, including acquisition, consolidation and retrieval. Memory can be modified further through reconsolidation and performance can change during extinction trials while the original memory remains intact. Recent studies of the molecular basis of these processes have found that many signaling molecules are involved in several stages of memory but, in some cases, molecular pathways may be selectively recruited only during certain stages of memory.
记忆通常被认为是一个具有多个阶段的过程，包括获取、巩固和检索。记忆可以通过重新巩固进一步改变，并且在消退试验期间表现会发生变化，而原始记忆保持完整。最近对这些过程的分子基础的研究发现，许多信号分子参与记忆的多个阶段，但在某些情况下，分子途径可能仅在记忆的特定阶段被选择性地激活。
