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在一个具有全国代表性的样本中,阈下及阈上DSM-IV广泛性焦虑障碍的一年患病率。

One-year prevalence of subthreshold and threshold DSM-IV generalized anxiety disorder in a nationally representative sample.

作者信息

Carter R M, Wittchen H U, Pfister H, Kessler R C

机构信息

Max Planck Institute of Psychiatry, Kraepelinstrasse 2, 80804 Munich, Germany.

出版信息

Depress Anxiety. 2001;13(2):78-88. doi: 10.1002/da.1020.

Abstract

Several studies of representative populations have reported prevalence rates of DSM-III and DSM-III-R generalized anxiety disorder (GAD); however, no community study has examined the effect of the stricter DSM-IV criteria on prevalence estimates and patterns of comorbidity. Furthermore, past studies based on "lifetime" symptom assessments might have led to upper-bound 1-year and point prevalence estimates. Data is presented from a national representative sample study of 4,181 adults in Germany, 18-65 years old, who were interviewed for DSM-IV disorders with the 12-month version of the Munich-Composite International Diagnostic Interview. The prevalence rate of strictly defined, 12-month threshold DSM-IV GAD was estimated to be 1.5%; however, 3.6% of respondents presented with at least subthreshold syndromes of GAD during the past 12 months. Higher rates of worrying and GAD were found in women (worrying 10%, GAD 2.7%) and in older respondents (worrying 9.3%, TAD 2.2%). Taking into account a wider scope of diagnoses than previous studies, a high degree of comorbidity in GAD cases was confirmed: 59.1% of all 12-month GAD cases fulfilled criteria for major depression, and 55.9% fulfilled criteria for any other anxiety disorder. In conclusion, prevalence and comorbidity rates found for DSM-IV GAD are not substantially different from rates reported for DSM-III-R GAD. The minor differences in our findings compared to previous reports are more likely attributable to differences in study methodology rather than changes in diagnostic criteria for DSM-IV.

摘要

几项针对代表性人群的研究报告了DSM-III和DSM-III-R广泛性焦虑障碍(GAD)的患病率;然而,尚无社区研究考察更严格的DSM-IV标准对患病率估计及共病模式的影响。此外,过去基于“终生”症状评估的研究可能导致了1年患病率和时点患病率的上限估计。本文呈现了一项针对德国4181名18至65岁成年人的全国代表性样本研究的数据,这些成年人接受了使用12个月版慕尼黑综合国际诊断访谈进行的DSM-IV障碍访谈。严格定义的、12个月阈值的DSM-IV GAD患病率估计为1.5%;然而,3.6%的受访者在过去12个月中至少出现了GAD的阈下综合征。女性(担忧10%,GAD 2.7%)和年长受访者(担忧9.3%,GAD 2.2%)中担忧和GAD的发生率更高。考虑到比以往研究更广泛的诊断范围,GAD病例中存在高度共病得到了证实:所有12个月GAD病例中有59.1%符合重度抑郁症标准,55.9%符合任何其他焦虑障碍标准。总之,DSM-IV GAD的患病率和共病率与DSM-III-R GAD报告的患病率并无实质性差异。与以往报告相比,我们研究结果中的细微差异更可能归因于研究方法的不同,而非DSM-IV诊断标准的变化。

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