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海兔烯,一种来自黑指纹海兔的新型溴代丙二烯,作为钠钾-ATP酶抑制剂。

Aplysiallene, a new bromoallene as an Na, K-ATPase inhibitor from the sea hare, Aplysia kurodai.

作者信息

Okamoto Y, Nitanda N, Ojika M, Sakagami Y

机构信息

Graduate School of Bioagricultural Sciences, Nagoya University, Japan.

出版信息

Biosci Biotechnol Biochem. 2001 Feb;65(2):474-6. doi: 10.1271/bbb.65.474.

DOI:10.1271/bbb.65.474
PMID:11302194
Abstract

A new bromoallene metabolite, named aplysiallene, was isolated from the Japanese sea hare, Aplysia kurodai, as an Na, K-ATPase inhibitor. Its structure was elucidated by spectroscopic methods. The known metabolites, laurinterol and debromolaurinterol, isolated from this animal were also evaluated for their Na, K-ATPase inhibitory activity.

摘要

从日本海兔(Aplysia kurodai)中分离出一种名为海兔二烯(aplysiallene)的新型溴代丙二烯代谢产物,作为一种钠钾-ATP酶抑制剂。通过光谱方法阐明了其结构。还对从该动物中分离出的已知代谢产物月桂萜醇(laurinterol)和脱溴月桂萜醇(debromolaurinterol)的钠钾-ATP酶抑制活性进行了评估。

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