肾球旁细胞瘤：一例报告
Juxtaglomerular cell tumor of the kidney: a case report.
作者信息
Min K O, Kwon H J, Ahn S J, Chang S A, Chang Y S, Bang B K, Kim J, Park M H, Jung E S, Choi Y J, Seo E J, Kim B K
机构信息
Department of Clinical Pathology, College of Medicine, the Catholic University of Korea, Seoul, Korea.
出版信息
J Korean Med Sci. 2001 Apr;16(2):233-6. doi: 10.3346/jkms.2001.16.2.233.
We report a case of renin-secreting juxtaglomerular cell tumor which developed in a hypertensive 47-yr-old Korean man. Presumptive clinical diagnosis was made before surgery based on the high level of plasma renin and the radiologic evidence of renal mass. Grossly, a round, bulging, well-encapsulated mass of 3 x 3 cm was located in the mid-portion of the right kidney. On microscopic examination, the tumor was composed of ovoid to polyhedral cells with bland nuclei, indistinct nucleoli and light eosinophilic cytoplasm. The immunostaining for renin showed strong positivity in the cytoplasm of tumor cells. The characteristic rhomboid shaped renin protogranules were observed in ultrastructural analysis.
我们报告一例发生于一名47岁韩国高血压男性的分泌肾素的球旁细胞瘤。术前根据血浆肾素水平升高及肾脏肿块的影像学证据做出了初步临床诊断。大体检查时，一个3×3 cm大小、圆形、隆起、包膜完整的肿块位于右肾中部。显微镜检查显示，肿瘤由卵圆形至多面体细胞组成，细胞核温和，核仁不明显，细胞质呈淡嗜酸性。肾素免疫染色显示肿瘤细胞胞质呈强阳性。超微结构分析观察到特征性的菱形肾素原颗粒。
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