Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea.
Department of Urology, Seoul National University Hospital, Seoul, Korea.
Kidney Res Clin Pract. 2014 Jun;33(2):106-8. doi: 10.1016/j.krcp.2014.03.001. Epub 2014 May 24.
Reninoma is a tumor of the renal juxtaglomerular cell apparatus that causes hypertension and hypokalemia because of hypersecretion of renin. We present a case of a 29-year-old female patient with reninoma and concomitant variant angina. The patient had uncontrolled hypertension and elevated plasma renin activity and aldosterone levels. Imaging studies revealed a mass in the left kidney, which was further confirmed as a renin-producing lesion via selective venous catheterization. During the evaluation, the patient had acute-onset chest pain that was diagnosed as variant angina after a provocation test. After partial nephrectomy, the plasma renin activity and plasma aldosterone levels decreased and blood pressure normalized. We report a case of reninoma with variant angina.
肾素瘤是一种位于肾小球旁器的肿瘤,由于肾素分泌过多会引起高血压和低钾血症。我们报告了一例 29 岁女性肾素瘤合并变异性心绞痛患者。该患者患有未控制的高血压,血浆肾素活性和醛固酮水平升高。影像学检查显示左肾有一肿块,通过选择性静脉导管插入术进一步证实为产生肾素的病变。在评估过程中,患者突发胸痛,激发试验后诊断为变异性心绞痛。行部分肾切除术,血浆肾素活性和血浆醛固酮水平下降,血压恢复正常。我们报告了一例伴有变异性心绞痛的肾素瘤。