Perera M G, Bernstein I L, Michael J G, Johansson S G
Am Rev Respir Dis. 1975 May;111(5):605-10. doi: 10.1164/arrd.1975.111.5.605.
The radioallergosorbent test was compared with currently accepted allergy diagnostic techniques in ragweed-sensitive and unselected patients. The radioallergosorbent test was positive in 28 of 30 patients with proved histories, positive scratch tests, and positive nasal provation tests to ragweed. The radioallergosorbent test was also positive in 69 per cent of 40 clinically sensitive patients whose diagnoses were corroborated by scratch tests alone. In unselected patients evaluated by intracutaneous testing with short ragweed extract, 10 minus 3 g per ml, the incidence of positive radioallergosorbent test scores was reduced to 43 per cent. No false positive results were encountered in these studies. A good relationship was observed between radioallergosorbent test scores and the maximal tolerable dose of ragweed administered during a course of "rush" immunotherapy in clinically allergic patients. These results suggest that the radioallergosorbent test has several unique advantages in assessing clinical sensitivity to ragweed.
在豚草敏感患者和未经挑选的患者中，将放射变应原吸附试验与目前公认的过敏诊断技术进行了比较。在30例有豚草确诊病史、划痕试验阳性且鼻激发试验阳性的患者中，有28例放射变应原吸附试验呈阳性。在40例仅通过划痕试验确诊的临床敏感患者中，69%的患者放射变应原吸附试验也呈阳性。在用浓度为每毫升10减3克的短豚草提取物进行皮内试验评估的未经挑选的患者中，放射变应原吸附试验阳性评分的发生率降至43%。在这些研究中未遇到假阳性结果。在临床过敏患者的“快速”免疫治疗过程中，观察到放射变应原吸附试验评分与给予豚草的最大耐受剂量之间存在良好关系。这些结果表明，放射变应原吸附试验在评估对豚草的临床敏感性方面具有几个独特的优势。
