Mel'man E P, Shutka B V
Arkh Anat Gistol Embriol. 1975 Feb;68(2):62-8.
The ultrastructural changes of the capillaries of the renal glomerule and the parenchyma of the kidney were studied in 20 albino rats after clamping the vascular peduncle of the left kidney for 30 minutes, 1, 2 and 3 hours without a following recovery of the blood flow. In 30 minutes pinocytosis was increased in the cytoplasm of endothelial cells of glomerule capillaries. In the cytopodia there appeared vacuoles. The brush border was swallen, its separate growings acquired a bulb-like shape. Microplasmatosis of the internal plasmolemma of the endothelium appeared after 1--2--3-hour ischemia. The basal layer of capillaries became wider, with uneven contours and partly homogenized. Cytopodia became deformed and more close. The brush border was rejected in some places. Mitochondria were swallen, crists lost their parallelism, their amount became less.
对20只白化大鼠进行研究，在不恢复血流的情况下，分别夹闭左肾血管蒂30分钟、1小时、2小时和3小时，观察肾小球毛细血管和肾实质的超微结构变化。夹闭30分钟时，肾小球毛细血管内皮细胞胞质内吞饮作用增强，胞质突起出现空泡，刷状缘肿胀，其单个生长物呈球状。缺血1 - 2 - 3小时后，内皮细胞内质膜出现微浆膜病。毛细血管基底层变宽，轮廓不均匀且部分均质化，胞质突起变形且更紧密，刷状缘在某些部位脱落，线粒体肿胀，嵴失去平行排列，数量减少。
