English J C, Patel P J, Greer K E
Department of Dermatology, University of Virginia, Charlottesville, USA.
J Am Acad Dermatol. 2001 May;44(5):725-43; quiz 744-6. doi: 10.1067/mjd.2001.114596.
Sarcoidosis is a systemic noncaseating granulomatous disorder of unknown origin. The cutaneous manifestations of sarcoidosis often enable the dermatologist to be the first physician to make the diagnosis. This article reviews essential sarcoidosis pathophysiology, clinical polymorphisms, systemic evaluation, and treatment modalities for cutaneous sarcoidosis to further enhance the dermatologist's understanding of this disease entity.
At the conclusion of this learning activity, participants should be familiar with the theories of the pathogenesis of sarcoidosis, its cutaneous manifestations, its various syndromes and associations, and its presentation in children. Participants should also be more knowledgeable about diagnostic evaluation, measurement of disease progression, treatment modalities, and the prognosis and mortality data of sarcoidosis.
结节病是一种病因不明的全身性非干酪样肉芽肿性疾病。结节病的皮肤表现常常使皮肤科医生成为首位做出诊断的医生。本文回顾结节病的基本病理生理学、临床多态性、全身评估以及皮肤结节病的治疗方式,以进一步增强皮肤科医生对这一疾病实体的理解。
在本学习活动结束时,参与者应熟悉结节病的发病机制理论、其皮肤表现、各种综合征及关联情况,以及在儿童中的表现。参与者还应更深入了解结节病的诊断评估、疾病进展的测量、治疗方式以及预后和死亡率数据。