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慢性鼓膜炎:患病率、临床表现及自然病程。

Chronic myringitis: prevalence, presentation, and natural history.

作者信息

Blevins N H, Karmody C S

机构信息

Department of Otolaryngology/Head Neck Surgery, Tufts University School of Medicine, New England Medical Center, Boston, Massachusetts, USA.

出版信息

Otol Neurotol. 2001 Jan;22(1):3-10. doi: 10.1097/00129492-200101000-00002.

DOI:10.1097/00129492-200101000-00002
PMID:11314712
Abstract

OBJECTIVE

The aim of this study was to examine the clinical presentation and natural history of chronic myringitis (CM).

STUDY DESIGN

Retrospective case review.

SETTING

Tertiary referral center.

PATIENTS

Chronic myringitis is defined as a loss of tympanic membrane epithelium for >1 month without disease within the tympanic cavity. Seven hundred fifty patient records were reviewed to determine the prevalence of CM in an academic otology practice. The records of 40 patients (45 ears) with CM seen between 1995 and 1999 inclusive were reviewed.

MAIN OUTCOME MEASURES

The series was reviewed with attention to previous medical and otologic history, the nature and duration of symptoms, the physical findings, and management.

RESULTS

The prevalence of CM was found to be -1% (approximately one fourth as common as cholesteatoma). Symptoms were often present for many years before the diagnosis of CM, with CM often mistaken for chronic otitis media. Sixty percent of patients had undergone previous otologic procedures. There did not appear to be an association between CM and systemic disease. Physical findings were varied, with granulation tissue and tympanic membrane perforations often occurring transiently. The clinical course of CM is typified by recurrent episodes of symptoms, often interspersed with long asymptomatic periods. A subset of CM can result in an acquired atresia. The most effective treatment appeared to be prolonged topical medications, surgery being reserved for only the most refractory cases.

CONCLUSIONS

Chronic myringitis is often mistaken for chronic otitis media. Such confusion prolongs the initiation of appropriate management and sometimes leads to needless tympanomastoid surgery. The otologist should be aware of this clinical entity and its varied presentation.

摘要

目的

本研究旨在探讨慢性鼓膜炎(CM)的临床表现及自然病程。

研究设计

回顾性病例分析。

研究地点

三级转诊中心。

患者

慢性鼓膜炎定义为鼓膜上皮缺失超过1个月且鼓室内无病变。回顾了750例患者的记录,以确定CM在学术性耳科实践中的患病率。对1995年至1999年期间(含)确诊的40例(45耳)CM患者的记录进行了回顾。

主要观察指标

回顾该系列病例,关注既往病史和耳科病史、症状的性质和持续时间、体格检查结果及治疗情况。

结果

发现CM的患病率约为1%(约为胆脂瘤患病率的四分之一)。CM的症状常在确诊前出现多年,常被误诊为慢性中耳炎。60%的患者曾接受过耳科手术。CM与全身性疾病之间似乎没有关联。体格检查结果各异,肉芽组织和鼓膜穿孔常呈一过性出现。CM的临床病程以症状反复发作、常夹杂着长时间无症状期为特征。一部分CM可导致后天性闭锁。最有效的治疗方法似乎是长期局部用药,手术仅用于最顽固的病例。

结论

慢性鼓膜炎常被误诊为慢性中耳炎。这种混淆会延长适当治疗的开始时间,有时会导致不必要的鼓室乳突手术。耳科医生应了解这种临床疾病及其多样的表现形式。

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