• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

难治性慢性弥漫性颗粒性鼓膜炎伴中耳道狭窄。

Refractory Chronic Diffuse Granular Myringitis with Medial Meatal Stenosis.

机构信息

Department of Otorhinolaryngology, Hospital Raja Permaisuri Bainun, Ipoh, Perak, Malaysia.

Department of Otorhinolaryngology, Universiti Malaya Faculty of Medicine, Kuala Lumpur, Malaysia.

出版信息

J Int Adv Otol. 2024 Sep 26;20(5):458-461. doi: 10.5152/iao.2024.231292.

DOI:10.5152/iao.2024.231292
PMID:39391172
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11562586/
Abstract

Granular myringitis is a chronic inflammatory condition of the tympanic membrane that does not involve the middle ear. Various treatment modalities have been proposed for the treatment of granular myringitis, but there is no standard treatment regime. A 60-year-old woman had left persistent ear discharge for 4 months. Examination revealed diffuse granulation tissue, forming a pseudomembrane at the medial aspect of the ear canal and obstructing the tympanic membrane. An audiogram revealed mild-to-moderate left-sided conductive hearing loss. She was treated with multiple courses of ear drop antibiotics but had no improvement. The decision for surgical intervention was driven by the presence of a grade IV medial meatal stenosis, the potential risks associated with prolonged medical management, the distressing impact on the patient's life, and a shared decision-making process. A combined transcanal and postauricular endoscopic approach whereby excision of the granulation tissue, canalplasty, and myringoplasty were performed. She exhibited complete symptom resolution and reported an improved quality of life. This approach yielded successful symptom resolution, highlighting its potential in managing refractory chronic granular myringitis. We aimed to carefully weigh the risks of surgery against its potential benefits in a refractory chronic case, acknowledging the inherent risks and disadvantages of surgical interventions. Further studies are warranted to evaluate the long-term outcomes and benefits of this approach.

摘要

鼓膜肉芽炎是一种不涉及中耳的慢性鼓膜炎症。已经提出了各种治疗方式来治疗鼓膜肉芽炎,但没有标准的治疗方案。一位 60 岁的女性左耳持续有耳漏已经 4 个月了。检查发现弥漫性肉芽组织,在耳道内侧形成假膜并阻塞鼓膜。听力图显示左侧中重度传导性听力损失。她曾接受多次耳部滴注抗生素治疗,但没有改善。由于存在 IV 级内耳道狭窄、长期药物治疗相关的潜在风险、对患者生活的困扰影响以及共同决策过程,决定进行手术干预。采用经耳道和耳后联合内镜方法,切除肉芽组织、耳道成形术和鼓膜成形术。她的症状完全缓解,生活质量得到改善。这种方法成功地缓解了症状,突出了其在治疗难治性慢性鼓膜肉芽炎方面的潜力。我们旨在仔细权衡手术的风险与其在难治性慢性病例中的潜在益处,同时认识到手术干预的固有风险和缺点。需要进一步的研究来评估这种方法的长期结果和益处。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4832/11562586/ec34cd78e743/jiao-20-5-458_f005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4832/11562586/f984202e3759/jiao-20-5-458_f001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4832/11562586/fc823589a103/jiao-20-5-458_f002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4832/11562586/b6d66d172f89/jiao-20-5-458_f003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4832/11562586/412012d86b8d/jiao-20-5-458_f004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4832/11562586/ec34cd78e743/jiao-20-5-458_f005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4832/11562586/f984202e3759/jiao-20-5-458_f001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4832/11562586/fc823589a103/jiao-20-5-458_f002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4832/11562586/b6d66d172f89/jiao-20-5-458_f003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4832/11562586/412012d86b8d/jiao-20-5-458_f004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4832/11562586/ec34cd78e743/jiao-20-5-458_f005.jpg

相似文献

1
Refractory Chronic Diffuse Granular Myringitis with Medial Meatal Stenosis.难治性慢性弥漫性颗粒性鼓膜炎伴中耳道狭窄。
J Int Adv Otol. 2024 Sep 26;20(5):458-461. doi: 10.5152/iao.2024.231292.
2
Combined tympanic epithelial layer avulsion and overlay myringoplasty for diffuse granular myringitis.联合鼓膜上皮层撕脱及覆盖式鼓膜成形术治疗弥漫性颗粒性鼓膜炎
J Laryngol Otol. 2010 Aug;124(8):842-5. doi: 10.1017/S0022215110000824. Epub 2010 Apr 7.
3
Canalplasty using underwater bone drilling in transcanal endoscopic myringoplasty for patients with a narrow external auditory canal.经耳道内镜鼓膜成形术中水下骨钻行鼓室成形术治疗外耳道狭窄患者。
Acta Otolaryngol. 2022 Jul-Aug;142(7-8):543-548. doi: 10.1080/00016489.2022.2099014. Epub 2022 Jul 27.
4
Acquired medial external auditory canal stenosis, anterior tympanomeatal angle blunting, and lateralized tympanic membrane: Nosology, diagnosis, and treatment.获得性外耳道内侧狭窄、鼓室前鼓耳道角变钝及鼓膜侧移:疾病分类、诊断与治疗
Eur Ann Otorhinolaryngol Head Neck Dis. 2019 Apr;136(2):93-97. doi: 10.1016/j.anorl.2018.12.002. Epub 2019 Jan 11.
5
Feasibility and advantages of transcanal endoscopic myringoplasty.经耳道内镜鼓膜成形术的可行性与优势
Otol Neurotol. 2014 Apr;35(4):e140-5. doi: 10.1097/MAO.0000000000000298.
6
Endoscopic Medial Reepithelization for Inflammatory Canal Stenosis.内镜下内侧再上皮化治疗炎性管腔狭窄。
Otol Neurotol. 2022 Sep 1;43(8):973-977. doi: 10.1097/MAO.0000000000003625.
7
Vinegar treatment in the management of granular myringitis.颗粒性鼓膜炎治疗中的醋疗法
J Laryngol Otol. 2002 Mar;116(3):176-80. doi: 10.1258/0022215021910474.
8
Acquired Stenosis of the External Ear Canal.后天性外耳道狭窄
Otolaryngol Clin North Am. 2023 Oct;56(5):919-931. doi: 10.1016/j.otc.2023.06.012. Epub 2023 Aug 6.
9
Endoscopy-aided laser therapy for intractable granular myringitis.
J Laryngol Otol. 2006 Jul;120(7):553-5. doi: 10.1017/S0022215106000739. Epub 2006 Mar 10.
10
Topical 5-fluorouracil for granular myringitis: a double-blinded study.外用5-氟尿嘧啶治疗颗粒性鼓膜炎:一项双盲研究。
J Laryngol Otol. 2010 Mar;124(3):279-84. doi: 10.1017/S0022215109992179. Epub 2009 Dec 11.

本文引用的文献

1
Efficacy of diluted vinegar in treating granular myringitis: a randomised controlled trial.稀释醋治疗粒状鼓膜炎的疗效:一项随机对照试验。
J Laryngol Otol. 2021 Jan;135(1):33-38. doi: 10.1017/S0022215120002716. Epub 2021 Jan 25.
2
Clinical characteristics of granular myringitis treated with castellani solution. Castellani 溶液治疗颗粒性鼓膜炎的临床特征。
Eur Arch Otorhinolaryngol. 2011 Aug;268(8):1139-1146. doi: 10.1007/s00405-011-1500-7. Epub 2011 Feb 5.
3
Granular myringitis: report of three prospective studies evaluating treatment options.
颗粒性鼓膜炎:三项评估治疗方案的前瞻性研究报告
Clin Otolaryngol. 2010 Jun;35(3):242-3. doi: 10.1111/j.1749-4486.2010.02118.x.
4
Combined tympanic epithelial layer avulsion and overlay myringoplasty for diffuse granular myringitis.联合鼓膜上皮层撕脱及覆盖式鼓膜成形术治疗弥漫性颗粒性鼓膜炎
J Laryngol Otol. 2010 Aug;124(8):842-5. doi: 10.1017/S0022215110000824. Epub 2010 Apr 7.
5
Topical 5-fluorouracil for granular myringitis: a double-blinded study.外用5-氟尿嘧啶治疗颗粒性鼓膜炎:一项双盲研究。
J Laryngol Otol. 2010 Mar;124(3):279-84. doi: 10.1017/S0022215109992179. Epub 2009 Dec 11.
6
[Experience of canalplasty during the overlay tympanoplasty].[覆盖式鼓室成形术中鼓室成形术的经验]
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2009 Feb;23(4):151-3.
7
Granular myringitis: Incidence and clinical characteristics.颗粒性鼓膜炎:发病率及临床特征
Otol Neurotol. 2006 Dec;27(8):1094-7. doi: 10.1097/01.mao.0000235379.72278.ed.
8
Endoscopy-aided laser therapy for intractable granular myringitis.
J Laryngol Otol. 2006 Jul;120(7):553-5. doi: 10.1017/S0022215106000739. Epub 2006 Mar 10.
9
Chronic myringitis: prevalence, presentation, and natural history.慢性鼓膜炎:患病率、临床表现及自然病程。
Otol Neurotol. 2001 Jan;22(1):3-10. doi: 10.1097/00129492-200101000-00002.
10
Granular myringitis: is it a surgical problem?颗粒性鼓膜炎:这是一个外科问题吗?
Am J Otol. 2000 Jul;21(4):462-7.