Frölich J, von Gontard A, Lehmkuhl G, Pfeiffer E, Lehmkuhl U
Klinik und Poliklinik für Psychiatrie und Psychotherapie des Kindes- und Jugendalters, Universität zu Köln Robert Koch Str. 10, 50931 Köln, Germany.
Eur Child Adolesc Psychiatry. 2001 Mar;10(1):54-7. doi: 10.1007/s007870170047.
Anorexia nervosa is an eating disorder that may be accompanied by cardiac symptoms of varying severity. So far disturbances like arrhythmias, mitral valve prolapse and loss of cardial ventricle mass have been described. Other somatic complications consist of electrolyte and acid-base imbalances, which in turn influence cardiac function. Between 1990 and 1999 we observed ten case reports from inpatient anorexic female adolescents, who developed pericardial effusions in the course of their illness. The diagnosis and course was revealed by echocardiography. No signs of heart failure could be noticed. In eight patients pericardial effusion remitted completely or partly by a concurrent increase in weight. A distinct pathophysiology for the development of pericardial effusion could not be revealed, but a correlation to restoration of weight seems to exist. Our report suggests that pericardial effusions are more frequent cardiac complications in anorexia nervosa than previously known. In most cases the clinical significance is doubtful.
神经性厌食症是一种饮食失调症，可能伴有不同严重程度的心脏症状。到目前为止，已经描述了诸如心律失常、二尖瓣脱垂和心室质量损失等紊乱情况。其他躯体并发症包括电解质和酸碱失衡，这反过来又会影响心脏功能。1990年至1999年间，我们观察了10例住院厌食症女性青少年的病例报告，她们在患病过程中出现了心包积液。通过超声心动图揭示了诊断和病程。未发现心力衰竭的迹象。8例患者的心包积液通过体重同时增加而完全或部分消退。心包积液发展的独特病理生理学尚不清楚，但似乎与体重恢复有关。我们的报告表明，心包积液是神经性厌食症中比以前所知更常见的心脏并发症。在大多数情况下，其临床意义值得怀疑。
