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躯体化特征可预测慢性广泛性疼痛的发作:一项基于大规模人群研究的结果。

Features of somatization predict the onset of chronic widespread pain: results of a large population-based study.

作者信息

McBeth J, Macfarlane G J, Benjamin S, Silman A J

机构信息

Arthritis Research Campaign Epidemiology Unit, School of Epidemiology and Health Sciences, University of Manchester, UK.

出版信息

Arthritis Rheum. 2001 Apr;44(4):940-6. doi: 10.1002/1529-0131(200104)44:4<940::AID-ANR151>3.0.CO;2-S.

Abstract

OBJECTIVE

Chronic widespread pain, the clinical hallmark of the fibromyalgia syndrome, is associated with other physical and psychological symptoms both in patients studied in a clinical setting and in those identified in the community. The present study was undertaken to examine the hypothesis that psychological and physical indicators of the process of somatization predict the development of new chronic widespread pain.

METHODS

In this population-based prospective study, 1,658 adults ages 18-65 years completed a detailed pain questionnaire, which included a pain drawing. They also completed the following psychosocial instruments: General Health Questionnaire, Somatic Symptom Checklist, Fatigue Questionnaire, and Illness Attitude Scales. Individuals were followed up at 12 months, at which time 1,480 (93% of subjects still living at their baseline address) provided data on pain status, using the same instruments.

RESULTS

At baseline, 825 subjects were classified as pain free and 833 as having pain not satisfying criteria for chronic widespread pain. Of those, 18 (2%) and 63 (8%), respectively, were classified as having chronic widespread pain at followup. After adjustment for age and sex, there were strong relationships between baseline test scores and subsequent risk of chronic widespread pain (odds ratio for the Somatic Symptom Checklist 3.3; odds ratio for the Illness Behavior subscale of the Illness Attitude Scales 9.0). All 95% confidence intervals excluded unity. These associations were independent of baseline pain status.

CONCLUSION

Subjects who are free of chronic widespread pain are at increased future risk of its development if they display other aspects of the process of somatization. Data from this population-based prospective study lend powerful support to the hypothesis that chronic widespread pain can be one manifestation of the somatization of distress.

摘要

目的

慢性广泛性疼痛是纤维肌痛综合征的临床标志,在临床研究的患者以及社区中确诊的患者中,均与其他身体和心理症状相关。本研究旨在检验躯体化过程的心理和身体指标可预测新的慢性广泛性疼痛发生这一假设。

方法

在这项基于人群的前瞻性研究中,1658名年龄在18至65岁的成年人完成了一份详细的疼痛问卷,其中包括一张疼痛图。他们还完成了以下心理社会测评工具:一般健康问卷、躯体症状清单、疲劳问卷和疾病态度量表。在12个月时对个体进行随访,此时1480名(93%仍居住在其基线地址的受试者)使用相同工具提供了疼痛状况数据。

结果

在基线时,825名受试者被分类为无疼痛,833名受试者的疼痛不符合慢性广泛性疼痛的标准。其中,分别有18名(2%)和63名(8%)在随访时被分类为患有慢性广泛性疼痛。在对年龄和性别进行调整后,基线测试分数与随后发生慢性广泛性疼痛的风险之间存在密切关系(躯体症状清单的优势比为3.3;疾病态度量表的疾病行为子量表的优势比为9.0)。所有95%置信区间均不包括1。这些关联独立于基线疼痛状况。

结论

无慢性广泛性疼痛的受试者如果表现出躯体化过程的其他方面,则未来发生该病的风险会增加。这项基于人群的前瞻性研究数据有力支持了慢性广泛性疼痛可能是痛苦躯体化的一种表现这一假设。

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