Wolfe Frederick, Rasker Johannes J
Research, National Data Bank for Rheumatic Diseases, Wichita, USA.
Internal Medicine, University of Kansas School of Medicine Wichita, Wichita, USA.
Cureus. 2021 Nov 29;13(11):e20010. doi: 10.7759/cureus.20010. eCollection 2021 Nov.
Fibromyalgia developed in the 1950s from a substrate of difficult to explain regional and widespread pain mixed with symptoms of psychosocial distress. Controversies regarding psychological issues were common. Multiple criteria arose to define the disorder, but each identified a different set of patients. The identification of widespread pain as a criterion changed the nature of the disorder by effectively eliminating regional pain as a component condition. The easy-to-measure and relatively reliable widespread pain criterion then came to define the disorder. In the primary care community, diagnostic criteria were largely ignored, and a substantial fraction of diagnosed patients with lower pain scores, particularly women and those with high non-pain symptom scores, were diagnosed. Non-pain symptoms were added back to the fibromyalgia definition and criteria in 2010. Recognition grew that fibromyalgia fit the description of a functional somatic disorder. The idea of fibromyalgia as a primary pain disorder with a neurobiological basis contended with fibromyalgia as a broader biopsychosocial disorder. It is increasingly recognized that fibromyalgia represents a dimensional, non-binary condition and that features of fibromyalgia extend to persons who do not satisfy the criteria. Severity assessments are now available but rarely used. The course of fibromyalgia is not well studied, and improvement and remission criteria have not been successfully defined. The future of fibromyalgia as a discrete disorder remains uncertain as features of fibromyalgia are increasingly observed in patients with multiple different medical conditions.
纤维肌痛症于20世纪50年代从一种难以解释的局部和广泛性疼痛的基础上发展而来,伴有心理社会困扰症状。关于心理问题的争议很常见。出现了多种标准来定义这种疾病,但每种标准所确定的患者群体都不同。将广泛性疼痛作为一项标准的确定改变了该疾病的性质,因为它有效地排除了局部疼痛作为一种构成条件。易于测量且相对可靠的广泛性疼痛标准随后开始用于定义该疾病。在初级保健领域,诊断标准在很大程度上被忽视,相当一部分疼痛评分较低的确诊患者,尤其是女性以及非疼痛症状评分较高的患者被诊断出来。2010年,非疼痛症状被重新纳入纤维肌痛症的定义和标准中。人们越来越认识到纤维肌痛症符合功能性躯体疾病的描述。纤维肌痛症作为一种具有神经生物学基础的原发性疼痛疾病的观点与纤维肌痛症作为一种更广泛的生物心理社会疾病的观点相互竞争。人们越来越认识到纤维肌痛症代表一种维度性、非二元性的病症,并且纤维肌痛症的特征也存在于那些不符合标准的人群中。现在有了严重程度评估,但很少使用。纤维肌痛症的病程尚未得到充分研究,改善和缓解标准也尚未成功确定。随着在多种不同疾病的患者中越来越多地观察到纤维肌痛症的特征,纤维肌痛症作为一种独立疾病的未来仍不确定。