Bruce M L
Department of Psychiatry, Weill Medical School of Cornell University, White Plains NY 10605, USA.
Am J Geriatr Psychiatry. 2001 Spring;9(2):102-12.
The author reviews evidence from epidemiologic and clinical studies suggesting a reciprocal, potentially spiraling, relationship between depression and disability in older adults. The discussion outlines possible methodological and conceptual explanations for this evidence and poses avenues for future research. An underlying theme is the impact of how disability and depression are measured on the nature of empirical evidence and its interpretation. Measures and corresponding analytic strategies that capture the complexity of depression, disability, and their relationship are expected to lead to the most fruitful approaches to reducing the burden of depression and disability in the lives of older adults.
作者回顾了流行病学和临床研究的证据，这些证据表明老年人的抑郁症与残疾之间存在一种相互的、可能呈螺旋式上升的关系。讨论概述了对此证据可能的方法学和概念性解释，并提出了未来研究的方向。一个潜在的主题是残疾和抑郁症的测量方式对实证证据的性质及其解释的影响。能够捕捉抑郁症、残疾及其关系复杂性的测量方法和相应的分析策略，有望带来最有效的方法，以减轻老年人生活中抑郁症和残疾的负担。
