Lenze E J, Rogers J C, Martire L M, Mulsant B H, Rollman B L, Dew M A, Schulz R, Reynolds C F
Department of Psychiatry, University of Pittsburgh School of Medicine, PA, USA.
Am J Geriatr Psychiatry. 2001 Spring;9(2):113-35.
Depression and anxiety disorders are associated with excess disability. The authors searched the recent geriatric literature for studies associating late-life depression or anxiety with physical disability. Studies showed depression in old age to be an independent risk factor for disability; similarly, disability was found to be a risk factor for depression. Anxiety in late life was also found to be a risk factor for disability, although not necessarily independently of depression. Increased disability due to depression is only partly explained by differences in socioeconomic measures, medical conditions, and cognition. Physical disability improves with treatment for depression; comparable studies have not been done for anxiety. The authors discuss how these findings inform current concepts of physical disability and discuss the implications for future intervention studies of late-life depression and anxiety disorders.
抑郁症和焦虑症与过度残疾相关。作者检索了近期老年医学文献，以寻找将晚年抑郁症或焦虑症与身体残疾相关联的研究。研究表明，老年抑郁症是残疾的独立危险因素；同样，残疾也被发现是抑郁症的危险因素。晚年焦虑症也被发现是残疾的危险因素，尽管不一定独立于抑郁症。抑郁症导致的残疾增加仅部分可由社会经济指标、医疗状况和认知方面的差异来解释。抑郁症得到治疗后身体残疾状况会改善；针对焦虑症尚未开展类似研究。作者讨论了这些发现如何为当前身体残疾的概念提供信息，并探讨了其对未来晚年抑郁症和焦虑症干预研究的意义。
