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尼泊尔人群中焦虑和抑郁的流行情况、决定因素和寻求治疗行为:对 2022 年尼泊尔人口与健康调查数据的二次分析。

Prevalence, determinants and care-seeking behaviour for anxiety and depression in Nepalese population: a secondary analysis of data from Nepal Demographic and Health Survey 2022.

机构信息

HERD International, Kathmandu, Nepal

Nepal Health Economics Association, Kathmandu, Nepal.

出版信息

BMJ Open. 2024 Aug 6;14(8):e078582. doi: 10.1136/bmjopen-2023-078582.

Abstract

OBJECTIVE

To determine the prevalence and factors associated with anxiety and depression and the care-seeking behaviour among Nepalese population.

DESIGN AND SETTINGS

Secondary analysis of the data from nationally representative Nepal Demographic and Health Survey 2022.

PARTICIPANTS

Analysed data of 12 355 participants (7442 females and 4913 males) aged 15-49 years.

OUTCOME MEASURES

Depression and anxiety were assessed using Patient Health Questionnaire-9 (PHQ-9) and Generalised Anxiety Disorder Assessment (GAD-7) tools, respectively.

STATISTICAL ANALYSIS

We performed weighted analysis to account for the complex survey design. We presented categorical variables as frequency, per cent and 95% confidence interval (CI), whereas numerical variables were presented as median, inter-quartile range (IQR) and 95% CI. We performed univariate and multivariable logistic regression to determine factors associated with anxiety and depression, and results were presented as crude OR (COR), adjusted OR (AOR) and their 95% CI.

RESULTS

The prevalence of depression and anxiety were 4.0% (95% CI 3.5 to 4.5) and 17.7% (95% CI 16.5 to 18.9), respectively. Divorced or separated participants were found to have higher odds of developing anxiety (AOR 2.40, 95% CI 1.74 to 3.31) and depression (AOR 3.16, 95% CI 1.84 to 5.42). Among ethnic groups, Janajati had lower odds of developing anxiety (AOR 0.77, 95% CI 0.65 to 0.92) and depression (AOR 0.67, 95% CI 0.49 to 0.93) compared with Brahmin/Chhetri. Regarding disability, participants with some difficulty had higher odds of developing anxiety (AOR 1.81, 95% CI 1.56 to 2.10) and depression (AOR 1.94, 95% CI 1.51 to 2.49), and those with a lot of difficulty had higher odds of anxiety (AOR 2.09, 95% CI 1.48 to 2.96) and depression (AOR 2.04, 95% CI 1.06 to 3.90) compared with those without any disability. Among those who had symptoms of anxiety or depression, only 32.9% (95% CI 30.4 to 34.4) sought help for the conditions.

CONCLUSIONS

Marital status and disability status were positively associated with anxiety and depression, whereas Janajati ethnicity had relatively lower odds of experiencing anxiety and depression. It is essential to develop interventions and policies targeting females and divorced individuals to help reduce the burden of anxiety and depression in Nepal.

摘要

目的

确定尼泊尔人口中焦虑和抑郁的流行率及其相关因素,以及寻求医疗的行为。

设计和设置

对 2022 年全国代表性尼泊尔人口与健康调查的数据进行二次分析。

参与者

分析了年龄在 15-49 岁的 12355 名参与者(7442 名女性和 4913 名男性)的数据。

结果测量

使用患者健康问卷-9(PHQ-9)和广泛性焦虑症评估量表(GAD-7)分别评估抑郁和焦虑。

统计分析

我们进行了加权分析,以考虑到复杂的调查设计。我们将分类变量表示为频率、百分比和 95%置信区间(CI),而数值变量则表示为中位数、四分位距(IQR)和 95%CI。我们进行了单变量和多变量逻辑回归,以确定与焦虑和抑郁相关的因素,结果以粗比值比(COR)、调整比值比(AOR)及其 95%CI 表示。

结果

抑郁和焦虑的患病率分别为 4.0%(95%CI 3.5 至 4.5)和 17.7%(95%CI 16.5 至 18.9)。离异或分居的参与者出现焦虑(AOR 2.40,95%CI 1.74 至 3.31)和抑郁(AOR 3.16,95%CI 1.84 至 5.42)的几率较高。在族裔群体中,与婆罗门/切特里族相比,贾纳杰蒂族出现焦虑(AOR 0.77,95%CI 0.65 至 0.92)和抑郁(AOR 0.67,95%CI 0.49 至 0.93)的几率较低。在残疾方面,有一定困难的参与者出现焦虑(AOR 1.81,95%CI 1.56 至 2.10)和抑郁(AOR 1.94,95%CI 1.51 至 2.49)的几率较高,而有很大困难的参与者出现焦虑(AOR 2.09,95%CI 1.48 至 2.96)和抑郁(AOR 2.04,95%CI 1.06 至 3.90)的几率较高,与无任何残疾的参与者相比。在出现焦虑或抑郁症状的人中,只有 32.9%(95%CI 30.4 至 34.4)寻求了对这些疾病的帮助。

结论

婚姻状况和残疾状况与焦虑和抑郁呈正相关,而贾纳杰蒂族出现焦虑和抑郁的几率相对较低。针对女性和离异者制定干预措施和政策,对于减轻尼泊尔的焦虑和抑郁负担至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a5fc/11308907/647e7605cda3/bmjopen-14-8-g001.jpg

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