Sutter E E
The Smith-Kettlewell Eye Research Institute, 2318 Filmore Street, San Francisco, CA 94115, USA.
Vision Res. 2001;41(10-11):1241-55. doi: 10.1016/s0042-6989(01)00078-5.
The multifocal m-sequence technique is a versatile set of tools for visual electrophysiology designed to provide access to the complex dynamic interplay of converging signals in the central nervous system. Here, a number of uses for the technique are demonstrated, with examples from human electroretinography. A simple relationship between the binary kernels extracted from a single experiment permits us to distinguish local from lateral interactions in the retina. Transformation of the series of binary kernels into response sequences provides new insight into unexpected fast dynamic properties of retinal responses and facilitates future modeling of the signals as well as identification of the signal sources.
多焦点m序列技术是一套用于视觉电生理学的通用工具,旨在揭示中枢神经系统中汇聚信号复杂的动态相互作用。本文通过人类视网膜电图的实例展示了该技术的多种用途。从单次实验中提取的二元核之间的简单关系,使我们能够区分视网膜中的局部相互作用和侧向相互作用。将一系列二元核转换为响应序列,为视网膜响应意外的快速动态特性提供了新的见解,并有助于未来对信号进行建模以及识别信号源。