Van Hien P, Kovács K, Matkovics B
Enzyme. 1975;19(1):1-4.
Consideration and comparison of specific superoxide dismutase activities shows that--of the values calculated for the same wet weight--the superoxide dismutase activity of the liver is more than twice that of the other tissues. This indicates the important metabolism-directing role of the liver. The large amount of superoxide dismutase (even the tissular superoxide dismutase alone) protects the tissues from the effects of the O(2)-radical, and the function of the superoxide dismutase probably opposing the cytochrome P-450 may be important as regards the hydroxylase effect.
对特定超氧化物歧化酶活性的考量与比较表明，在针对相同湿重计算得出的数值中，肝脏的超氧化物歧化酶活性是其他组织的两倍多。这表明肝脏在代谢调控中具有重要作用。大量的超氧化物歧化酶（即使仅为组织中的超氧化物歧化酶）可保护组织免受O₂⁻自由基的影响，并且超氧化物歧化酶可能与细胞色素P - 450相互拮抗的功能在羟化酶效应方面可能很重要。
